Cold agglutinin disease secondary to severe SARS-CoV-2 treated with eculizumab
Impaired immune response with uncontrolled inflammation and various immunological disorders have been reported during SARS-CoV-2 infection. Here, we report a case of cold agglutinin disease occurring during a severe coronavirus disease 2019 (COVID-19) in
Yachar Dawudi +3 more
semanticscholar +1 more source
Overexpression of Nictaba-like lectin genes from glycine max confers tolerance towards Pseudomonas syringae infection, aphid infestation and salt stress in transgenic Arabidopsis plants [PDF]
Plants have evolved a sophisticated immune system that allows them to recognize invading pathogens by specialized receptors. Carbohydrate-binding proteins or lectins are part of this immune system and especially the lectins that reside in the ...
Smagghe, Guy +2 more
core +6 more sources
Clinical characteristics and outcome of patients with autoimmune hemolytic anemia (AIHA) uniformly defined as primary by a diagnostic work-up [PDF]
Primary autoimmune hemolytic anemia (P-AIHA) is a relatively uncommon and hetereogeneous disease characterized by the destruction of red blood cells due to anti-erythrocyte autoantibodies (AeAbs) in the absence of an associated disease [1–3].
ARMIENTO, DANIELE +15 more
core +1 more source
Distribution of glycan motifs at the surface of midgut cells in the cotton leafworm (Spodoptera littoralis) demonstrated by lectin binding [PDF]
Glycans are involved in many biological phenomena, including signal transduction, cell adhesion, immune response or differentiation. Although a few papers have reported on the role of glycans in the development and proper functioning of the insect midgut,
Els J. M. Van Damme +5 more
core +2 more sources
AbstractPrimary chronic cold agglutinin disease (CAD) is a well-defined clinicopathologic entity in which a specific, clonal lymphoproliferative B-cell bone marrow disorder results in autoimmune hemolytic anemia. The immune hemolysis is entirely complement-dependent, predominantly mediated by activation of the classical pathway and phagocytosis of ...
openaire +2 more sources
Glucocorticoid-Responsive Cold Agglutinin Disease in a Patient with Rheumatoid Arthritis
A 57-year-old man with rheumatoid arthritis developed severe anemia during treatment with adalimumab plus methotrexate. Cold agglutinin disease was diagnosed because haptoglobin was undetectable, cold agglutinin was positive (1 : 2048), and the direct ...
Kyoko Honne +4 more
doaj +1 more source
Cold agglutinin disease after COVID‐19 vaccine
A 45-year-old female presented to the emergency department with a 1-week history of shortness of breath, palpitations, fatigue and dark urine. The symptoms had developed 3 days after she received the first dose of COVID-19 vaccine (Pfizer).
S. A. Aoun, Ibraheem Motabi
semanticscholar +1 more source
The role of CDC48 in the retro-translocation of non-ubiquitinated toxin substrates in plant cells [PDF]
When the catalytic A subunits of the castor bean toxins ricin and Ricinus communis agglutinin (denoted as RTA and RCA A, respectively) are delivered into the endoplasmic reticulum (ER) of tobacco protoplasts, they become substrates for ER ...
Aldo Ceriotti +69 more
core +2 more sources
A sixty year old male presented with dark urine, symptomatic anaemia and peripheral gangrene following cold exposure. Investigations revealed that he had haemolysis and serological evidence of recent Epstein Barr virus infection. Although acrocyanosis is
Karunarathne Suneth +4 more
doaj +1 more source
Cold agglutinin disease revisited: A multinational, observational study of 232 patients.
We retrospectively studied 232 patients with cold agglutinin disease (CAD) at 24 centers in five countries. In Norway and a northern region of Italy, the study was close to being population-based.
S. Berentsen +22 more
semanticscholar +1 more source

