Coronavirus Disease 2019 and Cold Agglutinin Syndrome: An Interesting Case.
European Journal of Case Reports in Internal Medicine, 2021 The coronavirus disease 2019 (COVID-19) pandemic has caused significant morbidity and mortality worldwide. While patients with COVID-19 most frequently present with pneumonia, respiratory failure and acute respiratory distress syndrome, increasing cases ...
Ruby Gupta +7 more
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Lactic acid bacteria isolated from poultry protect the intestinal epithelial cells of chickens from in vitro wheat germ agglutinin-induced cytotoxicity [PDF]
, 2018 Poultry fed on wheat-based diets regularly ingest wheat germ agglutinin (WGA) that has toxic effects in vitro on intestinal epithelial cells (IEC) obtained from 14-d-old broilers.
Apella, Maria Cristina +4 more
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Cold Agglutinin-Mediated Autoimmune Hemolytic Anemia in Association with Antiphospholipid Syndrome
Acta Haematologica, 2021 Antiphospholipid syndrome and cold agglutinin-mediated autoimmune hemolytic anemia are 2 distinct immune-mediated hematologic disorders. While no clear association exists between these 2 entities, complement activation is known to occur in both of them ...
R. Gelman +3 more
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Cold agglutinin disease: A case report with atypical clinical findings
SAGE Open Medical Case Reports, 2023 A female in her 60s presented to the allergy and immunology clinic for further investigation of ongoing dermatitis. She presented with chronic acrocyanosis, mainly in her left lower extremity, extending distally from her mid thigh with concurrent ...
Warren Balaja +2 more
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Seasonal variation in the incidence of cold agglutinin disease in Norway, Denmark, and Italy
American journal of hematology/oncology, 2021 characterization and detailed annotation of induction clinical course. Recently, the Ferrara criteria have been shown to predict early posttreatment mortality and OS in a heterogenous group of myeloid neoplasm patients receiving several different ...
D. Hansen +5 more
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Sutimlimab in Patients With Cold Agglutinin Disease (
European Journal of Haematology, EarlyView.ABSTRACT Cold agglutinin disease (CAD) is a low‐grade lymphoproliferative disorder accounting for 15%–30% of patients suffering from autoimmune hemolytic anemias. The clonal B cells produce autoantibodies primarily of the IgM‐κ class that cause agglutination of red blood cells (RBCs) at temperatures ≤ 37°C and activate the classical complement pathway ...
Sandra Maria Frey +5 more
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Obinutuzumab for the Treatment of Cold Agglutinin Disease: A Case Report [PDF]
Turkish Journal of HematologySiyuan Li, Kaini Shen, Lu Zhang
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The evolving management algorithm for the patient with newly diagnosed cold agglutinin disease
Expert Review of HematologyIntroduction Cold agglutinin disease (CAD) is driven by IgM autoantibodies reactive at 80% of patients, but not active on cold-induced peripheral symptoms.
W. Barcellini, B. Fattizzo
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Increased risk of thrombotic events in cold agglutinin disease: A 10‐year retrospective analysis
Research and Practice in Thrombosis and Haemostasis, 2020 Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia mediated by IgM autoantibodies that trigger hemolysis via classical complement pathway.
C. Broome +6 more
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CureusAutoimmune hemolytic anemia (AIHA) and hemophagocytic lymphohistiocytosis (HLH) are rare complications of infectious mononucleosis. The authors describe a 12-year-old male with acute infectious mononucleosis, hepatitis, cholestasis, and an autoimmune ...
Beatriz Sousa Nunes +3 more
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