Results 21 to 30 of about 4,360 (175)
Coomb's negative cold agglutinin disease: A rare report of an incidentally detected case
Asian Journal of Transfusion Science, 2021 Cold agglutinin disease (CAD) is a rare type of autoimmune hemolytic anemia which usually results due to production of immunoglobulin M-type autoantibody against the I/i and H antigens on red blood cell membrane.
K V Vinu Balraam +3 more
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Hematology, 2016 AbstractPrimary chronic cold agglutinin disease (CAD) is a well-defined clinicopathologic entity in which a specific, clonal lymphoproliferative B-cell bone marrow disorder results in autoimmune hemolytic anemia. The immune hemolysis is entirely complement-dependent, predominantly mediated by activation of the classical pathway and phagocytosis of ...
openaire +2 more sources
Glucocorticoid-Responsive Cold Agglutinin Disease in a Patient with Rheumatoid Arthritis
Case Reports in Rheumatology, 2015 A 57-year-old man with rheumatoid arthritis developed severe anemia during treatment with adalimumab plus methotrexate. Cold agglutinin disease was diagnosed because haptoglobin was undetectable, cold agglutinin was positive (1 : 2048), and the direct ...
Kyoko Honne +4 more
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Anaesthetic management for cardiac surgery in patients with cold haemagglutinin disease
Indian Journal of Anaesthesia, 2018 Cold haemagglutination is a primary or acquired autoimmune disease involving antibodies that lead to agglutination of red blood cells at low temperature followed by complement fixation and haemolysis on rewarming.
Jasbir S Khanuja +3 more
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Sutimlimab in Cold Agglutinin Disease
New England Journal of Medicine, 2021 Cold agglutinin disease is a rare autoimmune hemolytic anemia characterized by hemolysis that is caused by activation of the classic complement pathway. Sutimlimab, a humanized monoclonal antibody, selectively targets the C1s protein, a C1 complex serine protease responsible for activating this pathway.We conducted a 26-week multicenter, open-label ...
Röth, Alexander +15 more
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Coronavirus Disease 2019 and Cold Agglutinin Syndrome: An Interesting Case
European Journal of Case Reports in Internal Medicine, 2021 The coronavirus disease 2019 (COVID-19) pandemic has caused significant morbidity and mortality worldwide. While patients with COVID-19 most frequently present with pneumonia, respiratory failure and acute respiratory distress syndrome, increasing cases ...
Ruby Gupta +7 more
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Roth spots, a case report of anemic retinopathy due to Epstein–Barr virus
The Pan-American Journal of Ophthalmology, 2023 Roth spots can occur as ophthalmological manifestations of systemic pathologies that compromise the retinal capillary endothelium. A case report of retinopathy due to hemolytic anemia secondary to Epstein–Barr virus is presented.
Alejandro Londoño +3 more
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Fatal cold agglutinin-induced haemolytic anaemia: a case report
Journal of Medical Case Reports, 2010 Introduction Cold agglutinin disease usually develops as a result of the production of a specific immunoglobulin M auto-antibody directed against the I/i and H antigens, precursors of the ABH and Lewis blood group substances, on red blood cells ...
Reverberi Roberto +2 more
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Impact of Anti-M on Grouping and Cross Matching: The Challenges Faced in Three Cases [PDF]
National Journal of Laboratory MedicineAnti-M, a frequently encountered antibody of the MNS blood group system, is commonly regarded as a naturally occurring saline agglutinin that can occasionally exhibit clinically significant behaviour.
Betsy Jonahs +4 more
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New Insights in the Pathogenesis and Therapy of Cold Agglutinin-Mediated Autoimmune Hemolytic Anemia
Frontiers in Immunology, 2020 Autoimmune hemolytic anemias mediated by cold agglutinins can be divided into cold agglutinin disease (CAD), which is a well-defined clinicopathologic entity and a clonal lymphoproliferative disorder, and secondary cold agglutinin syndrome (CAS), in ...
Sigbjørn Berentsen
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