Results 61 to 70 of about 9,473 (270)
Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination [PDF]
, 2017 Effective bidirectional signalling between axons and Schwann cells is essential for both the development and maintenance of peripheral nerve function. We have established conditions by which human induced pluripotent stem cell-derived sensory neurons can
Bennett, David L.H. +5 more
core +2 more sources
Developmental Dynamics, EarlyView.Abstract Background To understand cellular morphology, biologists have relied on traditional optical microscopy of tissues combined with tissue clearing protocols to image structures deep within tissues. Unfortunately, these protocols often struggle to retain cell boundary markers, especially at high enough resolutions necessary for precise cell ...
Sam C. P. Norris +2 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely +14 more
wiley +1 more source
Case Reports in Hematology, 2019 Cold agglutinin disease (CAD) is an autoimmune hemolytic anemia and a distinct, clonal bone marrow lymphoproliferative disorder, characterized in most cases by a monoclonal IgMκ serum protein.
Øystein Sefland +2 more
doaj +1 more source
Case Reports in Hematology, 2023 Background. Mixed warm/cold autoimmune hemolytic anemia (AIHA) is a rare diagnostic entity with limited therapeutic options. Previous literature has described the diagnostic difficulty in this pathology and the limited response rates to corticosteroids ...
Elliot C. Smith +2 more
doaj +1 more source
Small Methods, EarlyView.This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto +12 more
wiley +1 more source
Adaptations and limitations of ring test for bovine brucellosis [PDF]
, 1954 Digitized 2007 AES.Includes bibliographical references (pages 41-43)
Herman, Harry August, 1905- +1 more
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British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Plasma glucocorticoids increase acutely after MI, thereafter tissue levels are amplified selectively within cells expressing 11‐ßhydroxysteroid dehydrogenase type 1 (11‐ßHSD1) that regenerates active glucocorticoids from circulating metabolites.
Sara Al Disi +19 more
wiley +1 more source
Autoimmune hemolytic anemia: current knowledge and perspectives
Immunity & Ageing, 2020 Autoimmune hemolytic anemia (AIHA) is an acquired, heterogeneous group of diseases which includes warm AIHA, cold agglutinin disease (CAD), mixed AIHA, paroxysmal cold hemoglobinuria and atypical AIHA.
Sylwia Sulimiera Michalak +5 more
doaj +1 more source
Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy. [PDF]
, 1988 Recently the minor B cell subpopulation that expresses the CD5 (Leu-1) antigen has been implicated as a source of IgM autoantibodies. Chronic lymphocytic leukemia (CLL), the most common leukemia in humans, represents a malignancy of small B lymphocytes ...
Carson, DA +3 more
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