Results 71 to 80 of about 8,940 (183)

What have transgenic and knockout animals taught us about respiratory disease? [PDF]

, 2000
Over the past decade there has been a significant shift to the use of murine models for investigations into the molecular basis of respiratory diseases, including asthma and chronic obstructive pulmonary disease.
AM Krieg, BJ O'Connor, DM Kemeny, G Cieslewicz, GJ Gleich, H Milgrom, J Bousquet, J Temelkovski, JA Elias, JK Sont, JM Drazen, JM Drazen, KG Tournoy, L Smith, LC Borish, M Mathur, M Saetta, ME Hyland, MJ Leckie, MP McLane, PK Jeffery, QA Hamid, R Callard, S Romagnani, SP Hogan, ST Holgate, TJ Torphy, TT Kung   +27 more
core   +2 more sources

P9‐34: Seasonal dynamics of cold airway hyperresponsiveness in asthma patients [PDF]

Respirology, 2021
openaire   +1 more source

Airway cell composition at rest and after an all-out test in competitive rowers [PDF]

, 2004
Med Sci Sports Exerc. 2004 Oct;36(10):1723-9. Airway cell composition at rest and after an all-out test in competitive rowers. Morici G, Bonsignore MR, Zangla D, Riccobono L, Profita M, Bonanno A, Paternò A, Di Giorgi R, Mirabella F, Chimenti L ...
AMATO G, BELLIA, Vincenzo, BENIGNO, Arcangelo, BONANNO A, BONSIGNORE G., BONSIGNORE, Maria Rosaria, CHIMENTI, Laura, DI GIORGI R, Mirabella, Fabio, MORICI, Giuseppe, PATERNO', Alessandra, PROFITA M, RICCOBONO, Laura, VIGNOLA, Antonio Maurizio, ZANGLA, Daniele   +14 more
core   +1 more source

Intranasal cold dry air is superior to histamine challenge in determining the presence and degree of nasal hyperreactivity in nonallergic noninfectious perennial rhinitis [PDF]

, 1998
The objective of the study was to compare cold dry air (CDA) and histamine in differentiating patients with nonallergic noninfectious perennial rhinitis (NANIPER) from control subjects.
Braat, J.P. (Joseph), Fokkens, W.J. (Wytske), Gerth van Wijk, R. (Roy), Mulder, P.G.H. (Paul), Rijntjes, E.   +4 more
core   +2 more sources

TRPM8 Expression in the Airway Epithelium Is Related to Cold-Induced Airway Hyperresponsiveness and Mucus Hypersecretion in Asthma [PDF]

D69. ASTHMA SUBPHENOTYPES, TARGETS AND THERAPEUTICS, 2020
D. Naumov, O. Kotova, D. Gassan, E. Afanaseva, E. Sheludko, V. Kolosov   +5 more
openaire   +1 more source

IFN-γ, IL-4 and IL-13 modulate responsiveness of human airway smooth muscle cells to IL-13 [PDF]

, 2008
Background: IL-13 is a critical mediator of allergic asthma and associated airway hyperresponsiveness. IL-13 acts through a receptor complex comprised of IL-13Rα1 and IL-4Rα subunits with subsequent activation of signal transducer and activator of ...
A Tomkinson, D Hebenstreit, D Kuperman, DA Kuperman, DS Faffe, DS Robinson, F Syed, G Grunig, G Grynkiewicz, GK Hershey, H Dickensheets, H Huang, H Ogata, HL Dickensheets, J Kellner, J Ohara, JA Losman, JC Laporte, K Espinosa, L Cohn, L Cohn, M Humbert, M Yoshida, MM Mentink-Kane, MO Daines, MO Daines, NM Heller, O Tliba, PE Moore, Q Chen, Q Peng, R Leigh, S Fichtner-Feigl, S Yamamoto, S Yasunaga, S Zuyderduyn, SA Shore, SJ Hirst, SO Rahaman, SP Hogan, SP Hogan, T Akimoto, T Naseer, T Sato, T Zheng, V Govindaraju, Z Huang, Z Zhu   +47 more
core   +4 more sources

Involvement of mitogen-activated protein kinases in mast cell mediator induced airway hyper-responsiveness in guinea pig trachea [PDF]

, 2016
Introduction: Exposure to allergens causes activation of mast cells and release of its mediators leading to airway constriction. Airway hyper-responsiveness (AHR) is a major characteristic of asthma but understanding of its causes is incomplete. Theories
Belikova, Maria
core  

Diagnostic work-up in patients with possible asthma referred to a university hospital [PDF]

, 2015
OBJECTIVE: The best strategy for diagnosing asthma remains unclear. Accordingly, the aim of this study was to evaluate diagnostic strategies in individuals with possible asthma referred to a respiratory outpatient clinic at a university hospital. METHODS:
Backer, Vibeke, Bødtger, Uffe, Porsbjerg, Celeste, Seersholm, Niels, Sverrild, Asger, Ulrik, Charlotte Suppli   +5 more
core   +2 more sources

Assessment of problematic severe asthma in children [PDF]

, 2010
Assessment of problematic severe asthma in children should be performed in a stepwise manner to ensure an optimal approach. A four-step assessment scheme is proposed.
Baraldi, E., Barbato, A., Bush, A., Carlsen, K. C. L., Carlsen, K. H., de Benedictis, F. M., De Jongste, J. C., Grp, Psaci, Hedlin, G., Malmstrom, K., Middelveld, R. J. M., Pedersen, S., Pedroletti, C., Piacentini, G. L., Pohunek, P., Wennergren, G.   +15 more
core   +1 more source

Pulmonary vasospasm in systemic sclerosis: noninvasive techniques for detection [PDF]

, 2014
In a subgroup of patients with systemic sclerosis (SSc), vasospasm affecting the pulmonary circulation may contribute to worsening respiratory symptoms, including dyspnea.
Giannarou, S, Hansell, DM, Keir, GJ, MacDonald, P, Nair, A, Oldershaw, P, Wells, AU, Wort, SJ, Yang, G-Z   +8 more
core   +1 more source