Results 231 to 240 of about 1,210,902 (300)

Molecular Dynamics Study of Hydrogen Release from NaH Using Machine Learning Potential. [PDF]

Materials (Basel)
Feng C, Zhang Y, Zhang X, Chang S, Zhang F, Cao L, Dong J, Wang R.   +7 more
europepmc   +1 more source

Consensus Formation and Change are Enhanced by Neutrality

Advanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag, Janina A. Hoffmann, Tim Rogers, Christian A. Yates   +3 more
wiley   +1 more source

Interfacial Thermal Transport and Phonon Scattering of Graphene and Graphene Oxide Embedded in Calcium Silicate Hydrate: A Molecular Dynamics Study. [PDF]

Nanomaterials (Basel)
Chen T, Chen D, Gong C, Zhao Y, Han Y, Wang Y.   +5 more
europepmc   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

Advanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng   +7 more
wiley   +1 more source

Structure of Water in the First Hydration Shell of the Highly Hydrophobic Anthracene. [PDF]

J Phys Chem A
Madrigal GA, Vasilopanagos C, Headen TF, Rosu-Finsen A, Chikani B, Talewar SK, Pardo LC, Salzmann CG.   +7 more
europepmc   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

First-Principles Study on the Magnetic Properties of Monolayer MOCl (M = Ti, V, Cr, Mo). [PDF]

Nanomaterials (Basel)
Pan Y, Wang Y.
europepmc   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Atomic-scale defect-mediated interfacial bonding in cold spray: FCC vs. BCC metal systems.

Appl Surf Sci Adv
Kardani A, Bagherifard S.
europepmc   +1 more source

3DICE: interpretable 3D cross-modal learning for drug-target interaction prediction and large-scale drug discovery. [PDF]

Bioinformatics
Liu AZR, Le NQK, Chua MCH.
europepmc   +1 more source