Results 51 to 60 of about 325,805 (288)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Three-body contact for fermions. I. General relations
We consider the resonant Fermi gas, that is, two-component fermions in three dimensions interacting by a short-range potential of large scattering length. We introduce a quantity, the three-body contact, that determines several observables.
Werner, Félix, Leyronas, Xavier
doaj +1 more source
Nanofiber-Mediated Interaction of Light with Cold Atoms
Light-matter interaction processes are extremely attractive for quantum information problems, where one of the main goals consists in a quantum state of light mapping into a collective atomic state.
Sheremet A.S. +4 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
We store and control ultra-cold atoms in a new type of trap using magnetic fields of vortices in a high temperature superconducting micro-structure. This is the first time ultra-cold atoms have been trapped in the field of magnetic flux quanta.
B Zhang +10 more
core +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Effective Field Theory for Cold Atoms
Effective Field Theory (EFT) provides a powerful framework that exploits a separation of scales in physical systems to perform systematically improvable, model-independent calculations.
Hammer, H. -W.
core +1 more source
Efimov physics in cold atoms [PDF]
57 pages, 13 figures, to appear in Annals of ...
Braaten, Eric, Hammer, H.-W.
openaire +2 more sources
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Cold atom microwave clock based on intracavity cooling in China space station
Atomic clocks with higher frequency stability and accuracy than traditional space-borne atomic clocks are the cornerstone of long-term autonomous operation of space-time-frequency systems.
Siminda Deng +11 more
doaj +1 more source

