Results 171 to 180 of about 10,751 (304)

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Cefdinir reprograms Gram‐positive bacteria to synergize with lysozyme against superbugs

open access: yesmLife, EarlyView.
Abstract Multidrug‐resistant (MDR) bacteria pose a critical global health threat, urgently requiring solutions. Cefdinir, the highest‐selling third‐generation cephalosporin but one now facing clinical obsolescence due to escalating resistance, is conventionally classified as a nascent cell wall synthesis inhibitor.
Qi Zhang   +6 more
wiley   +1 more source

Biogeography and diversification patterns in the Irano‐Turanian biodiversity hotspots inferred from a molecular phylogeny of the subendemic Iris subgenus Scorpiris (Iridaceae)

open access: yesNordic Journal of Botany, EarlyView.
The Irano‐Turanian Floristic Region harbors a rich flora, but our understanding of the development of this diversity is limited by a lack of data on phylogenetic relationships and biogeographic patterns of endemic and more widespread plants. Hypotheses of in situ diversification versus allopatric diversification were tested using Iris subgen. Scorpiris,
Mona Salimbahrami   +4 more
wiley   +1 more source

Capacity and limitations of US wild meat donation programmes

open access: yesPeople and Nature, EarlyView.
Abstract Historically, sharing of wild harvests to facilitate food security followed concepts of kin selection and reciprocal altruism. However, cultural shifts have reduced access to foods for some populations in modern times. Cultural altruism through sustainably harvested wild meat donation programmes (WDPs) can reduce food and nutritional ...
David S. Mason   +4 more
wiley   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan   +5 more
wiley   +1 more source

Laser induced ionising collisions with cold metastable neon

open access: yes, 2009
Modification of the ionising collision rate is demonstrated with cold (~1 mK) metastable neon (Ne*) 3P2 gas in a magneto-optical trap (MOT). A laser tuned close to the 3P2 to 3D3 cooling transition is used as a 'catalysis' to induce collisions between a ...
Laban, Dane, Sang, Robert, Glover, Rohan
core  

Proteome‐Wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights Into Early Immune Signaling

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim   +4 more
wiley   +1 more source

Yeast elongation factor homolog New1 protects a subset of mRNAs from degradation by no-go decay. [PDF]

open access: yesNucleic Acids Res
Müller M   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy