Results 191 to 200 of about 801,925 (377)

Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang, Jihana Achour, Laila Emam, Younes Louaguenouni, Catherine Cailleau, Françoise Mercier‐Nomé, Séverine Domenichini, Claudine Delomenie, Sezen Gul, Juliette Vergnaud, Nicolas Tsapis, Arnaud Mansart, Djillali Annane, Francois Fay, Elias Fattal   +14 more
wiley   +1 more source

Brightest Cluster Galaxy Offsets in Cold Dark Matter

The Open Journal of Astrophysics
The distribution of offsets between the brightest cluster galaxies of galaxy clusters and the centroid of their dark matter distributions is a promising probe of the underlying dark matter physics.
Cian Roche, Michael McDonald, Josh Borrow, Mark Vogelsberger, Xuejian Shen, Volker Springel, Lars Hernquist, Ruediger Pakmor, Sownak Bose, Rahul Kannan   +9 more
doaj   +1 more source

Peculiar velocities of galaxy clusters: a comparison of mixed dark matter and low-density cold dark matter [PDF]

, 1994
Rupert A. C. Croft, G. Efstathiou
openalex   +1 more source

Engineering Cortical Networks: An Open Platform for Controlled Human Circuit Formation and Synaptic Analysis In Vitro

Advanced Healthcare Materials, EarlyView.
An advanced on‐chip cortical network platform merges human stem cell‐derived neurons with microfabricated devices, enabling precise large‐format circuit design, optogenetic control, and molecular dissection of synaptic formation. This innovative system offers a powerful new tool to explore and model brain connectivity, disease mechanisms, can serve as ...
Pacharaporn Suklai, Taylor Minckley, Cathleen Hagemann, Karolina Faber, Rosalind Norkett, Ludovica Guetta, Kelly O'Toole, Bethany Geary, Michael J. Devine, Andrea Serio   +9 more
wiley   +1 more source

Functionalized Reduced Graphene Oxide‐Based Nanocomposite Hydrogels for Enhanced Osteogenesis in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Charge‐opposed reduced graphene oxide fillers are co‐integrated into biopolymeric nanocomposite scaffolds, synergistically enhance osteogenesis. Multiscale characterization reveals how surface chemistry and porosity dictate ectopic mineral architecture.
George Mihail Vlăsceanu, Cătălina Ionela Zamfir, Cornel Baltă, Hildegard Herman, Alina Ciceu, Maria Alexandra Duma, Mariana Ioniță, Roxana‐Cristina Popescu, Anca Hermenean   +8 more
wiley   +1 more source

B Non-Conservation, Cold Dark Matter and Subpreon Model [PDF]

, 1990
H. Senju
openalex   +1 more source

Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies

Advanced Healthcare Materials, EarlyView.
PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall, Safaa Naiel, Quan Zhou, Pareesa Ali, Tamana Rubina Yousof, Emily Wong, Ricardo Couto, Byron Yépez, Bernhard Seifried, Paul Moquin, Rod Rhem, Myrna Dolovich, Martin Rainer Kolb, Kjetil Ask, Todd Hoare   +14 more
wiley   +1 more source

Synergistic Combination of Tamoxifen–Tetraphenylethylene Co‐Assembled Micelles and Orlistat‐Induced Lipid Droplet Inhibition to Overcome Tamoxifen Resistance

Advanced Healthcare Materials, EarlyView.
Molecule 2, which contains a shorter oligoether chain, binds to tamoxifen via structural similarity forming micelles with a positive surface charge, thereby enhancing cellular uptake. These fluorescent micelles induce lipid droplet (LD) accumulation, exhibit strong fluorescence, and effectively overcome tamoxifen resistance by synergizing with orlistat‐
Jung Yeon Park, Jeehee Lee, Young Yong Kim, Sanghee Lee, Yongju Kim   +4 more
wiley   +1 more source

Strong gravitational lensing by $$Sgr A^*$$ S g r A ∗ and $$M87^*$$ M 87 ∗ black holes embedded in dark matter halo exhibiting string cloud and quintessential field

European Physical Journal C: Particles and Fields
We investigate the strong gravitational lensing phenomena caused by a black hole with a dark matter halo in the presence of cloud string and quintessence.
Niyaz Uddin Molla, Himanshu Chaudhary, G. Mustafa, Farruh Atamurotov, Ujjal Debnath, Dhruv Arora   +5 more
doaj   +1 more source

The evolution of large-scale structure in a universe dominated by cold dark matter

, 1985
M. Davis, G. Efstathiou, C. Frenk, S. White   +3 more
semanticscholar   +1 more source