Results 241 to 250 of about 685,122 (335)

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

Advanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma, Zhenbo Han, Jooman Park, Gege Yan, Sen Zhang, Youjeong Kwon, Sarath Babu Nukala, Jindpreet Kandola, Sandra Pinho, Chong Wee Liew, Yuwei Jiang, Sang‐Ging Ong   +11 more
wiley   +1 more source

Cold bonding of aluminium to copper by deformation-enhanced diffusion. [PDF]

Sci Rep
Vullum PE, Celotto A, Grong Ø, Holmestad R.   +3 more
europepmc   +1 more source

NIHAO IX: the role of gas inflows and outflows in driving the contraction and expansion of cold dark matter haloes [PDF]

, 2016
Aaron A. Dutton, Andrea V. Macciò, Avishai Dekel, Liang Wang, Gregory S. Stinson, Aura Obreja, Arianna Di Cintio, Chris B. Brook, Tobias Buck, Xi Kang   +9 more
openalex   +1 more source

Tumor‐Derived CDC37 Inhibits Antigen Cross‐Presentation in Dendritic Cells and Impairs Anti‐Tumor Immunity in Breast Cancer

Advanced Science, EarlyView.
Extracellular vesicle (EV)‐packaged CDC37 are released from TMBhiCTLlo breast cancer cells with high CDC37 expression, and internalized into endo/phagosomes of dendritic cells (DCs). Within these compartments, CDC37 locked HSP90–antigen complex, preventing antigen release into the cytosol.
Ruxin Wang, Yunyi Zhang, Xiangyu Meng, Jianli Zhao, Yue Xing, Qian Ouyang, Ning Zhang, Huiping Chen, Nanyan Miao, Erwei Song, Di Huang   +10 more
wiley   +1 more source

Influence of temperature on selenium mobility under contrasting redox conditions: a sediment flow-through reactor experiment. [PDF]

Biogeochemistry
Laberge-Carignan A, Mercier F, Larivière D, Couture RM.   +3 more
europepmc   +1 more source

The Cold Dark Matter Search test stand warm electronics card

, 2010
B. A. Hines, Denver Colorado U., Sten Hansen, M. E. Huber, T. Kiper, Wolfgang Rau, Kingston Queen's U., T. Saab, Florida, D. N. Seitz, K. M. Sundqvist, Berkeley Uc, V. Mandic, Minnesota   +13 more
openalex   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Volumetric response after closure of a spinal CSF leak in patients with spontaneous intracranial hypotension: a multicompartmental longitudinal study. [PDF]

J Neurointerv Surg
Zander C, Lützen N, Rau A, Wolf K, Arnold P, Mast H, El Rahal A, Volz F, Cimflova P, Beck J, Urbach H, Demerath T.   +11 more
europepmc   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Turning Mushy Lipids into Fruity Notes: Unlocking Lactone Biosynthesis Potential in Fat Industry Lipid Waste. [PDF]

Foods
Małajowicz J, Wierzchowska K, Jasińska K, Fabiszewska A.   +3 more
europepmc   +1 more source