Results 231 to 240 of about 55,316 (261)

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Ultrafine Airborne Particle Deposition and Clearance in an Avian Lung under Ecologically Relevant Conditions. [PDF]

Environ Sci Technol
Garcia Dominguez S, Jönsson L, Nord A, Preger C, Messing ME, Isaksson C, Rissler J.   +6 more
europepmc   +1 more source

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

Structural equation modeling reveals proline as the dominant pathway governing rice seed germination under chilling stress. [PDF]

Front Plant Sci
Cheng S, Luo H, Chen Z, Liu Z, Li P, Yu C, Xu X, Wen L, Peng X.   +8 more
europepmc   +1 more source

Physiological and Molecular Mechanisms of Nano-Hydroxyapatite (nHAP) in Regulating Chilling Tolerance of Cucumber Seedlings. [PDF]

Int J Mol Sci
Anwar W, Cai RH, Pang T, Li Y, Dissanayaka DDNV, Lai YS.   +5 more
europepmc   +1 more source

When context matters: community and environmental context to elicit natural products. [PDF]

Essays Biochem
Cumsille A, Putnam JHI, Chevrette MG.
europepmc   +1 more source

Characterisation of cold-selective lamina I spinal projection neurons in the mouse. [PDF]

Elife
Razlan AN, Ma W, Dickie AC, Polgar E, McFarlane AG, Yadav M, Cooper AH, Strathdee D, Watanabe M, Bell AM, Todd AJ, Hachisuka J.   +11 more
europepmc   +1 more source

Quantum-memory-assisted on-demand microwave-optical transduction. [PDF]

Nat Commun
Tu HT, Liao KY, Qiu SY, Liu XH, Guo YQ, Du ZQ, Xu Y, Zhang XD, Yan H, Zhu SL.   +9 more
europepmc   +1 more source

Regional mapping of CSF1R-positive microglia in neurodegenerative diseases and progressive MS, with exploratory presynaptic marker analyses. [PDF]

J Neuroinflammation
Bavarsad MS, Pereira FL, Reinhardt MM, Satpati A, Spina S, Seeley WW, Jagust W, Rabinovici GD, Green A, Grinberg LT.   +9 more
europepmc   +1 more source