Results 121 to 130 of about 280,496 (307)
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Predicting the Ultimate Axial Load Capacity of Joints formed using V-Band Retainers
V-band retainers are widely used in the automotive, aircraft and aerospace industries to connect a pair of circular flanges to provide a joint with good axial strength and torsional rigidity.
Müller, Matthias
core
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Finite element analysis of forward extrusion of 1010 steel
, 2009 Reliability of FE simulation of metal forming processes depends critically on the proper definition of material properties, the friction boundary conditions and details of the FE approach.
Olejnik, L. +2 more
core
Studies on the cold hardiness of the peach-potato aphid Myzus persicae (Sulzer) [PDF]
, 1985 A system incorporating a prototype automatic thermoelectric cooling method with computer-based recording of aphid supercooling points was developed and formed the basis of cold hardiness assessment. Under laboratory culture all developmental stages of
O'Doherty, Rose
core
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
RESEARCH ON THE IMPACT OF FRICTION COEFFICIENT TO SCALE IN COLD ROLL-BEATING FORMING
Jixie qiangdu, 2017 Scale of forming surface in cold roll-beating forming process is a major defect. Controlling scaly defects is an important method to improve forming surface quality.
FENG JingMin +3 more
doaj
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
, 2015 Cold forging processes are of great importance in production engineering due to the high material utilization and the associated energy and resource efficiency. Liquid and solid lubricants are used in order to perform cold forging processes successfully.
Bobzin, Kirsten
core
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source