Results 101 to 110 of about 1,899,113 (252)
Single point incremental forming of cold-rolled polycarbonate sheets
, 2019 The present work aims to examine the influence of a preliminary cold-rolling of polycarbonate sheets on the single point incremental forming of this outstanding engineering material.
Langella, A. +9 more
core +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Stabilizer bars: Part 3. Production methods [PDF]
Transport Problems, 2011 The article outlines the methods of stabilizer bar production as well as selected issues concerning the theory of cold roll forming. A proper construction and the selection of parameters are fundamental factors influencing the selection of a suitable ...
Adam-Markus WITTEK +2 more
doaj
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Análise do processo de estampagem de chapas de aço através da curva limite de conformação [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Ciência e Engenharia de Materiais, Florianópolis, 2009O presente trabalho teve como objetivo aplicar na indústria de eletrodomésticos da ...
Bastos, Alexandre Lundgren
core
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Cold forming techniques for the manufacture of steel structural sections
, 2008 Cold-formed steel structural sections are manufactured by using various cold forming processes such as cold-roll forming, brake pressing, bend braking, etc.
Heiyantuduwa, M. A. +2 more
core +3 more sources
Design and Analysis of Involute Spline Cold Roll Forming Machine
Jixie chuandong, 2019 At present， the design and manufacture of the domestic spline cold roll forming machine are mainly based on the experimental data， and theoretical studies are still insufficient.
Yanyang Wang +5 more
doaj
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source