Results 31 to 40 of about 269,095 (265)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A Review on Galling of Aluminum in Cold Forming Processes
Düzce Üniversitesi Bilim ve Teknoloji DergisiAs world’s sustainability become the most influential topic, aluminum and its alloys are becoming the preferred material of the automotive industry because they allow vehicle weight to be reduced without compromising safety.
Hatice Sandallı, Mert Özdoğan
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Bulletin of the New Zealand Society for Earthquake Engineering, 1985 This paper is the result of deliberations of the Society's Study Group for the seismic design of steel structures.
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
MATEC Web of Conferences, 2018 In order to reduce friction and wear in cold forging of aluminium and its alloys a tremendous amount of lubricants is used. The main task of the liquid lubricants is the separation of tool and workpiece surfaces to avoid adhesion and abrasion.
Teller Marco +7 more
doaj +1 more source
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2018 Civataüretiminin kritik prosesi olan ısıl işlem prosesi; soğuk şekillendirilenmalzemenin metalografik ve mekanik özelliklere olan etkisinin araştırılması,hem proses verimi hemde ürün performans kriterleri açısındandeğerlendirildiğinde sektörde deneysel ...
ALPER Baygut +2 more
doaj +1 more source
Micromachines, 2021 Compared to alternative production methods, cold forming offers technological, economic and ecological potential for the mass production of microgears.
Andreas Rohrmoser +2 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source