Results 151 to 160 of about 3,566,597 (273)

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

Advanced Science, EarlyView.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song, Peilin Han, Jiaming Li, Xiaolong Li, Xiang Zhang, Jing Fan, Dongliang Liu, Jianfa Cai, Lingchao Zhang, Jun Wu   +9 more
wiley   +1 more source

Plaque‐Hepatic Targeting Nanotherapy Disrupts the PCSK9‐LOX‐1 Axis to Suppress oxLDL in Atherosclerosis

Advanced Science, EarlyView.
Self‑amplifying PCSK9–LOX‑1 feedback axis drives atherosclerotic progression by promoting oxLDL generation and endothelial uptake. A dual‑targeting nanoplatform (siPCSK9@PEAL NPs‑aL) is constructed to simultaneously silence hepatic PCSK9 for lipid lowering and block plaque LOX‑1 for anti‑inflammation.
Yi Duan, Yijie Qiu, Yan Zhu, Quan Wang, Jiangtao Lin, Yourong Duan, Qi Wang, Yi Dong   +7 more
wiley   +1 more source

Neutral wind data obtained by the Medium frequency (MF) radar at the EISCAT Tromso radar site

, 2013
Neutral wind velocity for altitudes of ~70-90 km obtained by the Medium frequency (MF) radar at the EISCAT Tromso radar site.
Shin-ichiro Oyama, Tomoaki Hori, Satonori Nozawa, ISEE IUGONET Metadata Management Group   +3 more
core  

An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli

Advanced Science, EarlyView.
An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni, Costantino Casale, Marika Sperduti, Nevio L. Tagliamonte, Giorgia Imparato, Loredana Zollo, Paolo A. Netti   +6 more
wiley   +1 more source

Galactic outflows and star-formation quenching: a JWST perspective. [PDF]

Astrophys Space Sci
Davies RL, Belli S.
europepmc   +1 more source

An Avalanche Effect Nanomodulator Triggers Cascade Ferroptosis/Cuproptosis for Immunosuppressive Microenvironment Remodeling

Advanced Science, EarlyView.
A nanomodulator called L‐Arginine/lificiguat@Copper‐hollow Prussian blue@Calcium phosphate nanoparticles is constructed to launch a self‐amplifying “avalanche effect” in tumor cells. The ensuing cascade, triggered by the acidic tumor microenvironment and near‐infrared light, induces calcium overload, generates a reactive oxygen species and reactive ...
Hongmei Zhou, Caixi Yu, Guilan Xu, Lijuan Liu, Yujia Liang, Yulin Liang, He Ding, Litu Zhang, Piaoping Yang, Chen Wang   +9 more
wiley   +1 more source

The effects of affect: Working memory, rumination and emotion reactivity - Insights from an affective n-back task. [PDF]

PLoS One
Skram NKG, Storvestre CG, Ronold EH, Johnson SL, Elliott MV, Allen KJD, Hammar Å.   +6 more
europepmc   +1 more source

INFLUENCE OF AQUEOUS MEDIUM TYPE ON HEREDITARY SUSCEPTIBILITY OF COLD DEFORMED HIGH-TENSILE WIRE TO CORROSION

, 2014
During operation there is interact of wire and wire products with various aggressive mediums, so it is important to know to what extent the consequences of cold deformation effect on interaction of the deformed metal with an aqueous medium of varying ...
Пушкина, О.В., Алимов, В.И., Дзюба, Т.В.   +2 more
core  

Versatile Co‐Engineering of Immunogenic Cell Death‐Primed Dead Tumor Cell Bodies With Tumor‐Activated MnO2 for cGAS‐STING‐Potentiated Personalized Immunotherapy

Advanced Science, EarlyView.
DTBEI@CS@MnO2, fabricated via modular electrostatic co‐engineering and photothermal/photodynamic immunogenic cell death, specifically responds to the acidic and GSH‐rich tumor microenvironment. This triggers the release of DTBEI that provides tumor antigens, DNA, and DAMPs, as well as the generation of Mn2+, thereby synergistically potentiating cGAS ...
Bolun Xu, Xuan Lu, Yuquan Wang, Haihua Ji, Ying Zhang, Yiqun Wan, Hao Wan   +6 more
wiley   +1 more source

Body Size-Related Thermal Acclimation and Underlying Gene Expression Mechanisms in Workers of the Red Fire Ant <i>Solenopsis invicta</i>. [PDF]

Insects
Xu J, Peng R, Song Y, Yang JM, Duan CY, Gao W.   +5 more
europepmc   +1 more source