Results 131 to 140 of about 246,652 (294)
3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence
Advanced Healthcare Materials, EarlyView.Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes +11 more
wiley +1 more source
Numerical simulation and its optimization of cold air pools in the Lanzhou Valley
Meteorological ApplicationsPersistent cold air pools (CAPs) trap pollutants in valleys for extended periods, leading to reduced visibility and increased air pollution within these valleys.
Minjin Ma +3 more
doaj +1 more source
Journal of Advances in Modeling Earth Systems, 2019 This is the first paper that analyzes data from atmosphere model intercomparison project‐type climate simulations using a cloud‐system‐resolving global nonhydrostatic model without cumulus parameterization focussing particulaly on the relationship ...
Akira T. Noda +5 more
doaj +1 more source
PRETZEL: Opening the Black Box of Machine Learning Prediction Serving Systems
, 2018 Machine Learning models are often composed of pipelines of transformations. While this design allows to efficiently execute single model components at training time, prediction serving has different requirements such as low latency, high throughput and ...
Chun, Byung-Gon +5 more
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Advanced Materials, EarlyView.A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen +16 more
wiley +1 more source
Assembling a True “Olympic Gel” From over 16 000 Combinatorial DNA Rings
Advanced Materials, EarlyView.Olympic gels are an elusive class of soft matter, consisting of molecular networks held together purely by mechanically interlocked rings. Their topological structure promises unique properties and functions, but their synthesis has proven notoriously difficult.
Sarah K. Speed +9 more
wiley +1 more source
Advanced Materials, EarlyView.An overview of design principles and scalable fabrication strategies for multifunctional bio‐based packaging. Radiative cooling films, modified‐atmosphere films/membranes, active antimicrobial/antioxidant platforms, intelligent optical/electrochemical labels, and superhydrophobic surfaces are co‐engineered from material chemistry to mesoscale structure
Lei Zhang +6 more
wiley +1 more source
Intellectual Property Management Strategies to Accelerate the Development and Access of Vaccines and Diagnostics: Case Studies on Pandemic Influenza, Malaria and SARS [PDF]
, 2006 Achieving global access to vaccines, diagnostics, and pharmaceuticals remains a challenge. Throughout the developing world, intellectual property (IP) constraints complicate access to critically essential medical technologies and products.
Eiss, Robert +3 more
core +1 more source
Advanced Materials, EarlyView.A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip +12 more
wiley +1 more source
Seamlessly Unifying Attributes and Items: Conversational Recommendation for Cold-Start Users
, 2021 Static recommendation methods like collaborative filtering suffer from the inherent limitation of performing real-time personalization for cold-start users.
Chua, Tat-Seng +5 more
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