Results 111 to 120 of about 66,872 (284)
Advanced Functional Materials, EarlyView.A molecular shielding strategy to convert “protein‐sticky” and “non‐tumor specific” clinical ICG dye, into a “low protein binding” and “tumor‐targeting” dye with prolonged blood circulation and renal clearance is described. These shielded ICGs demonstrate strong tumor accumulation and optimal tissue clearance, resulting in high tumor‐to‐background ...
Li Xiang +9 more
wiley +1 more source
Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation
Advanced Healthcare Materials, EarlyView.This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad +7 more
wiley +1 more source
Convective Self‐Aggregation As a Cold Pool‐Driven Critical Phenomenon [PDF]
Geophysical Research Letters, 2019 AbstractConvective self‐aggregation is when thunderstorm clouds cluster over a constant temperature surface in radiative convective equilibrium. Self‐aggregation was implicated in the Madden‐Julian Oscillation and hurricanes. Yet, numerical simulations succeed or fail at producing self‐aggregation, depending on modeling choices. Common explanations for
openaire +3 more sources
The Evolution and Life Cycle of Valley Cold Pools [PDF]
, 2015 Despite our increased understanding in the relevant physical processes, forecasting radiative cold pools and their associated meteorological phenomena (e.g. fog and freezing rain) remains a challenging problem in mesoscale models.
Wilson, Travis Harold
core
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Neutrophil‐Mimetic MRI Enables Ultra‐Early Detection of Vascular Inflammation After Stroke
Advanced Healthcare Materials, EarlyView.In this study, we developed neutrophil‐mimetic MRI probes that detect ultra‐early neuroinflammation following ischemic stroke by targeting E‐selectin. Within seconds of their injection, these microparticles mimic initial leukocyte adhesion to the activated cerebral endothelium.
Marion Isabelle Morvan +17 more
wiley +1 more source
Advanced Materials, EarlyView.Elephant‐skin‐inspired crack networks are programmed in porous diatomaceous earth (DE)‐cement composites using substrate‐guided, stress‐concentration induced fracture. The resulting crack lattices act as capillary conduits that redistribute water, while the porous matrix stores moisture.
Qingya Huang +5 more
wiley +1 more source
Journal of Advances in Modeling Earth Systems, 2019 This is the first paper that analyzes data from atmosphere model intercomparison project‐type climate simulations using a cloud‐system‐resolving global nonhydrostatic model without cumulus parameterization focussing particulaly on the relationship ...
Akira T. Noda +5 more
doaj +1 more source
Advanced Materials, EarlyView.Oxygen‐releasing hydrogels are widely used to support cell survival in 3D cultures and to promote wound healing. However, incorporating catalase to convert H2O2 into O2 often generates additional oxygen bubbles, leading to material instability which rarely addressed.
Sukulya Bunuasunthon +3 more
wiley +1 more source
Upper Ocean Response to the Atmospheric Cold Pools Associated With the Madden-Julian Oscillation
, 2010 Atmospheric cold pools are frequently observed during the Madden‐Julian Oscillation events and play an important role in the development and organization of large‐scale convection.
Pei, Suyang +3 more
core +3 more sources