Results 21 to 30 of about 258,564 (253)

E2F transcription factor 5, a new regulator in adipogenesis to mediate the role of Krüppel-like factor 7 in chicken preadipocyte differentiation and proliferation

Poultry Science
: E2F transcription factor 5 (E2F5) gene is a transcription factor, plays an important role in the development of a variety of cells. E2F5 is expressed in human and mouse adipocytes, but its specific function in adipogenesis is unclear.
Ziqiu Jia, Zhao Jin, Meiqi Li, Xin Zhang, Min Peng, Shanshan Zhang, Ming Tan, Qingzhu Yang, Weiyu Wang, Yingning Sun   +9 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Effects of rescue gloves on hand skin temperature and manual performance under local cold exposure

环境与职业医学
BackgroundCold environments reduce work efficiency and increase the risk of frostbite. ObjectiveTo investigate the effects on cold protection and manual performance of rescue gloves in cold environments, and to preliminarily verify the feasibility of ...
Xiaoxue YAN, Qian WANG, Aike GUAN, Jie YANG   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Willingness to pay to protect cold water corals [PDF]

Conservation Biology, 2019
Abstract There is increasing pressure to use currently untapped resources in the deep sea, raising questions regarding ecosystem service trade‐offs in these often unknown areas. We assessed the trade‐offs between protection of cold‐water coral reefs and economic activities, such as fisheries and petroleum extraction, through a survey ...
Armstrong, Claire W, Aanesen, Margrethe, Rensburg, Thomas M, Sandorf, Erlend Dancke   +3 more
openaire   +5 more sources

Transcriptome Analysis of the Response of Aphis glycines Feeding on Ambrosia artemisiifolia

Agronomy
Common ragweed, Ambrosia artemisiifolia L., a noxious invasive plant, produces novel secondary metabolites. However, it attracts soybean aphid, Aphis glycines, a significant pest of soybean, to feed on it.
Xue Han, Changchun Dai, Jian Liu, Zhenqi Tian   +3 more
doaj   +1 more source

A TRICk to Improve the Effectiveness of RIC: Role of Limb Temperature in Enhancing the Effectiveness of Remote Ischemic Conditioning

Biology, 2022
Background: Treatment of myocardial ischemia/reperfusion (IR) injury is still an unmet clinical need. A large variability of remote ischemic conditioning (RIC) protection has been reported; however, no studies have considered the temperature of the ...
Claudia Penna, Matteo Sorge, Francesca Tullio, Stefano Comità, Saveria Femminò, Mara Brancaccio, Pasquale Pagliaro   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Expression of Heat Shock Protein 90 Genes Induced by High Temperature Mediated Sensitivity of Aphis glycines Matsumura (Hemiptera: Aphididae) to Insecticides

Insects
Soybean aphid, Aphis glycines Matsumura (Hemiptera: Aphididae), is a major pest of soybean fields. While high-temperature stress induced by global warming can initially suppress aphid populations, these pests may eventually adapt, leading to more severe ...
Xue Han, Yulong Jia, Changchun Dai, Xiaoyun Wang, Jian Liu, Zhenqi Tian   +5 more
doaj   +1 more source