Results 81 to 90 of about 5,221,850 (348)

Resistance in Superconductors [PDF]

, 2010
In this pedagogical review, we discuss how electrical resistance can arise in superconductors. Starting with the idea of the superconducting order parameter as a condensate wave function, we introduce vortices as topological excitations with quantized ...
Abrikosov A. A., Berezinskii V. L., Bertrand I. Halperin, Bulgadaev S., de Gennes P. G., Eugene Demler, Giamarchi T., Gil Refael, Greiner M., Ivanchenko Y. M., José J. V., Korshunov S., Korshunov S., Likharev K. K., Likharev K. K., Maki K., Nakamura Y., Sarma S. D., Schön G., Simanek E., Tinkham M.   +20 more
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Cold resistance of plants of Vitex L. species in introduction conditions of M.M. Gryshko National Botanical Garden of the NAS of Ukraine

Інтродукція Рослин, 2014
The results of Vitex L. species cold resistance, based on 3-years researches, are given. The peculiarities of plant biology have been find out, that result in introducents damage by frost –30 and –35 °С.
N.Ya. Levchyk, D.G. Makarova, O.I. Kytajev, V.A. Kryvoshapka, D.B. Rahmetov   +4 more
doaj   +1 more source

Trehalose-6-Phosphate Synthase Contributes to Rapid Cold Hardening in the Invasive Insect Lissorhoptrus oryzophilus (Coleoptera: Curculionidae) by Regulating Trehalose Metabolism

Insects, 2023
Rapid cold hardening (RCH) is known to rapidly enhance the cold tolerance of insects. Trehalose has been demonstrated to be a cryoprotectant in Lissorhoptrus oryzophilus, an important invasive pest of rice in China.
Juhong Zhang, Lizhong Qi, Baoyu Chen, Hongye Li, Lianglin Hu, Qingtai Wang, Shang Wang, Jinghui Xi   +7 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Electrical resistivity near Pomeranchuk instability in two dimensions

, 2006
We analyze the DC charge transport in the quantum critical regime near a d-wave Pomeranchuk instability in two dimensions. The transport decay rate is linear in temperature everywhere on the Fermi surface except at cold spots on the Brillouin zone ...
G. Rickayzen, I. J. Pomeranchuk, Luca Dell’Anna, Walter Metzner   +3 more
core   +1 more source

Slowing-Down in the Radiator and Cherenkov Radiation Angular Distributions from Relativistic Heavy Ions at FAIR, SPS and LHC energies [PDF]

, 2007
An adaptive learning algorithm using laser velocity meter is proposed for the process control of tandem cold mills. This method is used for on-line adaptive learning calculation of deformation resistance of strip and rolling friction models.
Bogdanov, O., Fiks, E., Geissel, H., Pivovarov, Y., Scheidenberger, C.   +4 more
core   +3 more sources

Transcriptomic analysis to uncover genes affecting cold resistance in the Chinese honey bee (Apis cerana cerana)

PLoS ONE, 2017
The biological activity and geographical distribution of honey bees is strongly temperature-dependent, due to their ectothermic physiology. In China, the endemic Apis cerana cerana exhibits stronger cold hardiness than Western honey bees, making the ...
Kai Xu, Qingsheng Niu, Huiting Zhao, Yali Du, Yusuo Jiang   +4 more
semanticscholar   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source