Results 111 to 120 of about 8,842,438 (372)

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Potential Impacts of Meteorological Variables on Acute Ischemic Stroke Onset

Risk Management and Healthcare Policy, 2020
Xuemei Qi,1 Zhongyan Wang,2 Xiaoshuang Xia,1 Juanjuan Xue,1 Yumeng Gu,1 Suqin Han,3 Lin Wang,2 Xin Li,1,* Sean X Leng4,* 1Department of Neurology, The Second Hospital of Tianjin Medical University, Tianjin, People’s Republic of China; 2Department ...
Qi X, Wang Z, Xia X, Xue J, Gu Y, Han S, Wang L, Li X, Leng SX   +8 more
doaj  

Neurosensory and vascular function after 14 months of military training comprising cold winter conditions

Scandinavian Journal of Work, Environment & Health, 2016
OBJECTIVE: This study aimed to examine the effects of 14 months of military training comprising cold winter conditions on neurosensory and vascular function in the hands and feet.
Daniel Carlsson, Hans Pettersson, Lage Burström, Tohr Nilsson, Jens Wahlström   +4 more
doaj   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Kination Dominated Reheating and Cold Dark Matter Abundance

, 2005
We consider the decay of a massive particle under the complete or partial domination of the kinetic energy density generated by a quintessential exponential model and we impose a number of observational constraints originating from nucleosynthesis, the ...
Agashe, Allahverdi, Baer, Baltz, Bassett, Bean, Bennett, Bélanger, Bélanger, Bœhm, C. Pallis, Caldwell, Catena, Cembranos, Chattopadhyay, Chattopadhyay, Cheng, Chung, Copeland, Covi, Cyburt, Davidson, de Garcia Maia, Dimopoulos, Dimopoulos, Drees, Edsjö, Ellis, Ellis, Ellis, Ellis, Ellis, Ellis, Ellis, Feng, Ferreira, Fornengo, França, Fujii, Fujii, Gardner, Gelmini, Gelmini, Gherghetta, Giovannini, Giudice, Goldberg, Gondolo, Gondolo, Gómez, Gómez, Hannestad, Joyce, Joyce, Kamionkowski, Kane, Kofman, Kofman, Kolb, Kolb, Lahanas, Lahanas, Lahanas, Lazarides, Lazarides, Liddle, Lyth, Matchev, McDonald, Moroi, Muñoz, Nagano, Nihei, Okada, Pallis, Pallis, Pallis, Peebles, Profumo, Riess, Sahni, Salati, Scherrer, Servant, Spergel, Spokoiny, Tegmark, Turner, Wetterich, Yahiro   +89 more
core   +3 more sources

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Fiber optic health monitoring and temperature behavior of bridge in cold region

, 2017
The objectives of this research are (a) to establish a structural health monitoring system for bridge safety evaluation that is suitable for cold, remote regions and (b) to identify the bridge responses under variations in temperature.
F. Xiao, J. L. Hulsey, R. Balasubramanian   +2 more
semanticscholar   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Critical correlations in an ultracold Bose gas revealed by means of a temporal Talbot-Lau interferometer

, 2013
We study experimentally the critical correlation in an ultra-cold Bose gas with a temporal Talbot-Lau (TL) interferometer. Near the critical temperature, we observe a bi-modal density distribution in an ultra-cold Bose gas after the application of the TL
Chen, Xuzong, Wu, Biao, Xiong, Hongwei, Xiong, Wei, Yue, Xuguang, Zhou, Xiaoji   +5 more
core   +1 more source

Impact of mitochondrial alternative oxidase expression on the response of Nicotiana tabacum to cold temperature.

Physiologia Plantarum : An International Journal for Plant Biology, 2011
The plant mitochondrial electron transport chain (ETC) includes a non-energy conserving alternative oxidase (AOX) thought to dampen reactive oxygen species (ROS) generation by the ETC and/or facilitate carbon metabolism by uncoupling it from ATP turnover.
Jia Wang, Nirusan Rajakulendran, S. Amirsadeghi, G. C. Vanlerberghe   +3 more
semanticscholar   +1 more source