Results 101 to 110 of about 981,828 (304)

A Second Cold War? Explaining Changes in the American Discourse on China: Evidence from the Presidential Debates (1960-2020). [PDF]

J Chin Polit Sci, 2023
Marandici I.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The first contacts between Lithuanian and Swedish orthopedic surgeons after the Cold War. [PDF]

Acta Orthop, 2022
Hansson N, Padrini G, Halling T, Söhner F.   +3 more
europepmc   +1 more source

Ten Miles from Richmond

, 2014
At the tiny crossroads town of Cold Harbor, Ulysses S. Grant hoped to crush Robert E. Lee\u27s army and hasten the war\u27s end.
Guelzo, Allen C.
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Oncolytic Adenoviruses: The Cold War against Cancer Finally Turns Hot. [PDF]

Cancers (Basel), 2022
Oronsky B, Gastman B, Conley AP, Reid C, Caroen S, Reid T.   +5 more
europepmc   +1 more source

Simple Shelters?: Monitoring Radioactive Fallout Across Canada, 1959–63 [PDF]

, 2012
During the early Cold War, the Canadian government adivsed public that they could cheaply build fallout shelters in their homes to protect their families from radiation after a nuclear war.
Burtch, Andrew
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Disaggregated Perspectives on Civil War and Ethnic Conflict : Prospects of an Emerging Research Agenda [PDF]

Journal on Ethnopolitics and Minority Issues in Europe, 2009
After the end of the Cold War, international relations scholars studying violent conflict took note of the fact that since 1945, the most common and lethal form of organized violence was intra- rather than interstate war.
Tim Dertwinkel
doaj  

The origin story of rapamycin: systemic bias in biomedical research and cold war politics. [PDF]

Mol Biol Cell, 2022
Powers T.
europepmc   +1 more source