Results 91 to 100 of about 32,437 (227)

Fibroblast Activation Protein Expression Differs Between Inflamed and Fibrostenotic Inflammatory Bowel Disease

JCC Plus, Volume 1, Issue 5, September 2026.
This study demonstrates that fibroblast activation protein expression is elevated in inflamed and fibrostenotic inflammatory bowel disease, with highest levels in fibrostenotic Crohn's disease. Cellular fibroblast activation protein predominates in inflamed tissues and localises to α‐SMA−PDPN−CD90+ stromal cells. ABSTRACT Background Intestinal fibrosis
Dalia A. Lartey, Bram W. van Os, Bo Jun Ke, Kelly van Wijnbergen, Gert de Hertogh, Luuk J. A. C. Hawinkels, Gianluca Matteoli, Jie Su, Christianne J. Buskens, Jarmilla D. W. van der Bilt, Geert R. A. M. D'Haens, Joep Grootjans, Manon E. Wildenberg, Marieke C. Barnhoorn, Mark Löwenberg   +14 more
wiley   +1 more source

Bronchiectasis as an Underrecognized Extraintestinal Manifestation of Inflammatory Bowel Disease

JCC Plus, Volume 1, Issue 5, September 2026.
ABSTRACT Introduction Inflammatory bowel diseases (IBD) are chronic inflammatory diseases of the gastrointestinal tract, often presenting with extraintestinal manifestations (EIMs). The most prevalent pulmonary EIM is IBD‐associated bronchiectasis (IBD‐BE), which is often overlooked.
Lynn te Slaa, Josje Altenburg, Mark Löwenberg   +2 more
wiley   +1 more source

Incidence and Prognostic Factors for Colectomy in Acute Severe Ulcerative Colitis with Concomitant CMV Infection

Diseases
Background/Objectives: Cytomegalovirus (CMV) is an opportunistic pathogen, complicating acute severe ulcerative colitis (ASUC), and its role in ASUC prognosis remains a debate.
Konstantina Kitsou, Konstantina Chalakatevaki, Georgios Kokkotis, Evgenia Papathanasiou, Vassiliki Kitsou, Spyridon Michopoulos, Evanthia Zampeli, Giorgos Bamias   +7 more
doaj   +1 more source

The rs10781468 Genetic Polymorphism of the Gαq (GNAQ) Gene Is Associated With Responsiveness to Opioid Analgesics in Patients With Postoperative and Cancer Pain: An Exploratory Study

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
In our exploratory hypothesis‐generating study using patients with postoperative pain and cancer pain, for rs10781468 in the GNAQ gene, the minor allele was associated with reduced opioid consumption and an increased pain threshold. ABSTRACT Background G protein–coupled receptors, the largest class of cell surface receptors, are ubiquitously expressed ...
Hiroaki Owada, Daisuke Nishizawa, Tsutomu Mieda, Miki Tsujita, Hideyuki Nakagawa, Shigeki Yamaguchi, Rikuhei Tsuchida, Yaeko Yokoshima, Akira Kitamura, Masakazu Hayashida, Ken‐ichi Fukuda, Tatsuya Ichinohe, Kazutaka Ikeda, Makoto Kurano, Masahiko Sumitani, Kanji Uchida   +15 more
wiley   +1 more source

Short‐term outcomes of intracorporeal anastomosis in laparoscopic colectomy for colon cancer: A nationwide, multi‐institutional cohort study in Japan (ICAN study)

Annals of Gastroenterological Surgery
Background Several randomized controlled trials and meta‐analyses have demonstrated the potential advantages of intracorporeal over extracorporeal anastomosis.
Tomohiro Yamaguchi, Keitaro Tanaka, Jun Watanabe, Hiroki Hamamoto, Atsushi Nishimura, Fumihiko Fujita, Hirokazu Suwa, Masaaki Ito, Kazushige Kawai, Junichiro Hiro, Seiichiro Yamamoto, Sho Nambara, Masato Ota, Yuri Ito, Junji Okuda, Masafumi Inomata, Masahiko Watanabe, Takeshi Naitoh, ICAN Collaborative Study Group of the Japan Society of Laparoscopic Colorectal Surgery   +18 more
doaj   +1 more source

Colectomy [PDF]

BMJ, 1895
openaire   +2 more sources

The “GABAergic Brake” on the Spinal Defecation Reflex: A Proposed Neurobiological Model Explaining Clozapine‐ and Benzodiazepine‐Induced Gastrointestinal Hypomotility and Ogilvie's Syndrome

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
Synergistic “Double Brake” Model on the Spinal Defecation Center in Clozapine‐Induced Constipation. Real‐world data shows BZDRs increase laxative risk in schizophrenia. Mitigating the central GABAergic brake via sedative optimization and maintaining gut microbiota homeostasis prevents fatal Ogilvie's syndrome.
Takahiko Nagamine
wiley   +1 more source

Management of congenital female genital tract anomalies related to primary amenorrhea and/or cyclic abdominal pain: A retrospective cohort study

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 9, Page 1810-1822, September 2026.
Overall, 21 patients with uterine, cervical, and vaginal aplasia were treated successfully with neovagina formation. In 6 out of 8 patients, with obstructed uterine cavity, anastomosis was successful; one underwent hysterectomy and one elective hemi‐hysterectomy.
Grigoris F. Grimbizis, Sofia Tsiapakidou, Eirini Iordanidou, Georgios Kioussis, Anastasia Vatopoulou, Theodoros Theodoridis   +5 more
wiley   +1 more source

Fatigue and Cognitive Impairment in Adults With Primary Sclerosing Cholangitis: Results From Concept Elicitation Interviews

Liver International, Volume 46, Issue 9, September 2026.
ABSTRACT Background and Aims To understand the experience of fatigue and cognitive impairment in adults with symptomatic primary sclerosing cholangitis (PSC) as an essential first step towards developing PSC‐specific symptom measures. Methods Purposeful sampling was used to identify 17 symptomatic adults from the PSC Symptom Assessment Project who met ...
Donna M. Evon, Kaya Merkler, Laura Mkumba, Nicole Lucas, Lauren Wright, Joanne Hatchett, Rachel Gomel, Patrick J. Smith, Sasha Deutsch‐Link, Christopher L. Bowlus, Mark G. Swain, Bryce B. Reeve   +11 more
wiley   +1 more source

Aseptic meningitis due to intravenous immunoglobulin therapy (IVIG) in therapy‐refractory pyoderma gangraenosum

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katharina A. Kälber, Knut Schäkel, Alexander Enk, Julia K. Winkler   +3 more
wiley   +1 more source