Results 111 to 120 of about 32,233 (231)

Sex Difference in Effect of the OPRM1 Gene A118G (rs1799971) Single‐Nucleotide Polymorphism on the Requirement for Postoperative Fentanyl in Japanese Patients Who Underwent Laparoscopic‐Assisted Colectomy

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
This study found that the OPRM1 A118G polymorphism was associated with sex‐specific differences in pain and opioid sensitivity among Japanese patients, highlighting a potential role of genotype‐by‐sex interaction in personalized pain management. ABSTRACT Background The A118G (rs1799971) single‐nucleotide polymorphism (SNP) of the OPRM1 gene, which ...
Hideyuki Nakagawa   +10 more
wiley   +1 more source

Understanding Patient and Gastroenterologist Preferences at the Time of Treatment Escalation to First‐Line Advanced Therapy in Ulcerative Colitis: A Discrete Choice Experiment in Five European Countries

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Background With guidelines recommending earlier advanced therapy (AT) use after 5‐ASA failure for patients with moderately‐to‐severely active ulcerative colitis (UC), it is important to explore treatment preferences at the point of escalation to first‐line AT.
Stefan Schreiber   +12 more
wiley   +1 more source

A Single Amino Acid Substitution in CspA Increases Germination Sensitivity and Broadens Bile Salt Germinant Specificity in Clostridioides difficile Spores

open access: yesEnvironmental Microbiology, Volume 28, Issue 6, June 2026.
In reservoir‐associated RT033 strains, we observe a natural rewiring of spore germination that lowers the activation threshold and broadens bile‐salt specificity, enabling germination at low germinant levels and in response to typically inhibitory bile‐salts common in animal hosts.
Isabel Roseiro   +7 more
wiley   +1 more source

Megacolon Associated with Multiple Endocrine Neoplasia Type 2B: A Case Successfully Managed with Ileostomy. [PDF]

open access: yesSurg Case Rep
Ikeda T   +12 more
europepmc   +1 more source

Utility of Urinary Extracellular Vesicles for Colorectal Cancer: Comparison of DNA Quality and MRD Detection

open access: yesCancer Science, Volume 117, Issue 6, Page 1667-1677, June 2026.
Urinary EVs provide highly pure vesicles with superior DNA quality, making them a robust and completely non‐invasive source for molecular profiling. Urinary EV‐DNA–based MRD assessment shows significant prognostic value and may serve as a practical tool for postoperative monitoring and risk stratification in colorectal cancer.
Shintaro Kanaka   +14 more
wiley   +1 more source

Temporal trends in colorectal resections for benign colorectal neoplasia: A retrospective cohort study of the ACS‐NSQIP 2016–2022

open access: yesColorectal Disease, Volume 28, Issue 6, June 2026.
Abstract Background Colorectal cancer (CRC) screening programmes in North America have effectively reduced CRC incidence. Among the nearly six million colonoscopies performed annually in the United States, 4%–11% detect large benign colorectal neoplasms, many of which can be removed endoscopically, minimizing the need for surgery. Endoscopic removal is
Sahil Sharma   +9 more
wiley   +1 more source

Intestinal ultrasound in acute severe ulcerative colitis treated with intravenous cyclosporine: case series. [PDF]

open access: yesCrohns Colitis 360
Miyatani Y   +4 more
europepmc   +1 more source

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