Este ensayo presenta una relectura de las teorías de la ciudad collage de Colin Rowe y Fred Koetter desde la perspectiva del Sur-Este Global y, en concreto, desde sus ciudades y barrios informales, donde 'la aparente combinación de lo esquizoide y lo ...
Lola Martínez-Fons
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Colin Rowe`s architectural dialectics
The article is devoted to the theoretical architectural heritage of Colin Rowe. The article examines the origins of the formation of a scientist’s thinking, based on the influence of two different scientific schools. Below are three of Rowe’s most significant essays on architectural issues.
Elina V. Danilova
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"Reckoning with Colin Rowe: ten architects take position"
Reckoning With Colin Rowe es un pequeño, pero muy inteligente y desinhibido, libro sobre Colin Rowe, publicado después de su fallecimiento y editado por el arquitecto, escritor y profesor Emmanuel Petit. En él se recogen una selección de textos realizados ex profeso por los siguientes autores: Robert Maxwell, Anthony Vidler, Peter Eisenman, O.
José Ángel Sanz Esquide
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Plasma biomarker progression across the Alzheimer's disease amyloid beta and tau positron emission tomography trajectories. [PDF]
Abstract INTRODUCTION With increased uptake in disease‐modifying treatments for amyloid beta (Aβ) removal, it is important to measure performance of highly sensitive plasma biomarkers to detect the presence of Aβ and tau in cognitively impaired populations.
Cánovas R +21 more
europepmc +2 more sources
Mesial temporal tau pathology impacts basal forebrain degeneration in early Alzheimer's disease. [PDF]
Abstract INTRODUCTION The cholinergic basal forebrain system, particularly the nucleus basalis of Meynert (Ch4), is selectively vulnerable to amyloid beta (Aβ) and tau in Alzheimer's disease (AD). Their interplay may be a critical driver of AD progression, but remains poorly understood. METHODS Data from 779 older individuals in the Australian Imaging,
Xia Y +10 more
europepmc +2 more sources
Harmonizing neuropsychological test data across prospective studies. [PDF]
Abstract INTRODUCTION Alzheimer's disease (AD) research relies on large datasets and advanced statistical models. However, individual population studies often lack sufficient sample size for conclusive results. Harmonizing cognitive test data across studies can address this gap, despite differences in testing protocols.
Shishegar R +21 more
europepmc +2 more sources
CenTauR correlation with amyloid, atrophy and cognition across the Alzheimer's Disease spectrum: A tau imaging study with 18F‐MK6240 PET [PDF]
Abstract Background The CenTauR (CTR) standard method for PET measurement of tau provides consistent results across tau tracers. This study establishes regional CTR thresholds for elevated tau and evaluates the CTR relationship with amyloid, neurodegeneration and cognition across the AD spectrum.
Rowe C +12 more
europepmc +3 more sources
Using AI to improve cross‐sectional and longitudinal Amyloid PET quantification: A validation study across 7 large cohorts [PDF]
Abstract Background Centiloid quantification relies on a Standardised Uptake Value Ratio (SUVR) that could be subject to noise, spill‐in, and specific binding in the reference region. We developed a novel deep learning method that learns scan‐specific variability from longitudinal trends to correct SUVR quantification and then validated it in 7 large ...
Bourgeat P +20 more
europepmc +3 more sources
Sensitivity of cognitive composite scores to amyloid accumulation in emergent Alzheimer's disease [PDF]
Abstract Background In clinical trials for preclinical Alzheimer's disease (AD), cognition is the primary outcome and is measured by preclinical Alzheimer's disease cognitive composite (PACC) scores that combine data from neuropsychological tests of memory and executive function and clinical mental status.
Xia Y +8 more
europepmc +2 more sources
Interpreting positive plasma Aβ42/40 results when amyloid PET is negative [PDF]
Abstract Background The agreement between plasma Aβ42/40 and Aβ‐PET is approximately 75%, with a large portion of discrepancies due to positive plasma with negative PET results. Questions remain about whether these reflect brain Aβ changes detectable in plasma before PET‐detectable.
Feizpour A +18 more
europepmc +3 more sources

