Results 41 to 50 of about 4,808 (173)

Characterization of a Coliphage AS1 isolated from sewage effluent in Pakistan

Brazilian Journal of Biology, 2021
The emergence of multi-drug resistant (MDR) bacterial strains, which are posing a global health threat has developed the interest of scientists to use bacteriophages instead of conventional antibiotics therapy.
A. Ullah, T. Qamash, F. A. Khan, A. Sultan, S. Ahmad, M. Abbas, M. A. K. Khattak, N. Begum, S. U. Din, J. Jamil, Kalsoom   +10 more
doaj   +1 more source

Virtual Screening of Bacteriocins From Lactic Acid Bacteria Against Monkeypox DNA Polymerase: Sakacin P and Mundticin KS Emerge as Promising Candidates

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Melisa Z. Karaman, Karan Goel, Fernando Berton Zanchi, Aykut Ozdarendeli, Somdutt Mujwar, Ahmet E. Yetiman, Ozkan Fidan   +6 more
wiley   +1 more source

Structural basis of transcription arrest by coliphage HK022 Nun in an Escherichia coli RNA polymerase elongation complex

eLife, 2017
Coliphage HK022 Nun blocks superinfection by coliphage λ by stalling RNA polymerase (RNAP) translocation specifically on λ DNA. To provide a structural framework to understand how Nun blocks RNAP translocation, we determined structures of Escherichia ...
Jin Young Kang, Paul Dominic B Olinares, James Chen, Elizabeth A Campbell, Arkady Mustaev, Brian T Chait, Max E Gottesman, Seth A Darst   +7 more
doaj   +1 more source

Recent Advances in the Molecular Mechanisms of Bacterial Anti‐Phage Defence Systems

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
Panoptes as an example for an antiphage system consists of OptS producing a cyclic dinucleotide that prevents activation of OptE, a transmembrane protein. Phage T4 infection introduces the sponge protein Acb2 that adsorbs the cyclic dinucleotide thus activating OptE which disrupts the cell membrane aborting phage infection.
Harald Brüssow
wiley   +1 more source

Characterization and complete genome analysis of a bacteriophage vB_EcoM_DE7 infecting donkey-derived Escherichia coli

Virus Research, 2022
A lytic bacteriophage vB_EcoM_DE7 (hereafter designated DE7) that could infect donkey-derived Escherichia coli was isolated. The bacteriophage was examined by transmission electron microscopy, and the result showed that DE7 belonged to the family ...
Jia-qi Cui, Wen-hua Liu, Ya-xin Zang, Can Zhang, Ling Zou, Hu-zhi Sun, Qiang Pan, Hui-ying Ren   +7 more
doaj   +1 more source

Microbial reductions and physical characterization of chitosan flocs when using chitosan acetate as a cloth filter aid in water treatment

PLoS ONE, 2022
The World Health Organization (WHO) estimates 2.1 billion people lack access to safely managed water. Cloth filtration is often employed in rural and developing communities of South Asia for point-of-use water treatment, but bacteria and viruses are too ...
Hemali H. Oza, Eleanor B. Holmes, Emily S. Bailey, Collin K. Coleman, Mark D. Sobsey   +4 more
doaj   +2 more sources

Oral Phage Therapy of Acute Bacterial Diarrhea With Two Coliphage Preparations: A Randomized Trial in Children From Bangladesh

EBioMedicine, 2016
Background: Antibiotic resistance is rising in important bacterial pathogens. Phage therapy (PT), the use of bacterial viruses infecting the pathogen in a species-specific way, is a potential alternative.
Shafiqul Alam Sarker, Shamima Sultana, Gloria Reuteler, Deborah Moine, Patrick Descombes, Florence Charton, Gilles Bourdin, Shawna McCallin, Catherine Ngom-Bru, Tara Neville, Mahmuda Akter, Sayeeda Huq, Firdausi Qadri, Kaisar Talukdar, Mohamed Kassam, Michèle Delley, Chloe Loiseau, Ying Deng, Sahar El Aidy, Bernard Berger, Harald Brüssow   +20 more
doaj   +1 more source

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, Volume 1, Issue 2, Page 63-89, June 2026.
ABSTRACT The growing recognition of the microbiome’s role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

Characterisation and In Planta Activity of Bacteriophages That Infect the Key Bacterial Species Associated With Acute Oak Decline

Microbial Biotechnology, Volume 19, Issue 6, June 2026.
Phages that infect the oak pathogens Brenneria goodwinii and Gibbsiella quercinecans were isolated. The phages were able to effectively reduce bacterial populations of their respective hosts in vitro. However, when applied in planta, the phages did not reduce host populations and instead phages and bacteria co‐existed over time.
Emily R. Grace, Vanja Milenkovic, Katherine G. Hinton, Sabrine Dhaouadi, Diana Vinchira‐Villarraga, Michael A. Brockhurst, Mojgan Rabiey, Robert W. Jackson   +7 more
wiley   +1 more source

Virological and bacteriological quality of drinking water in Ethiopia

Applied Water Science, 2018
Since unsafe water is responsible for many illness, deaths, and economic failure, water quality monitoring is essential. A cross-sectional study was conducted on 218 drinking waters samples collected between February and June 2016 to assess water quality
Tesfaye Legesse Bedada, Walelign Dessie Mezemir, Firehiwot Abera Dera, Waktole Gobena Sima, Samson Girma Gebre, Redwan Muzeyin Edicho, Almaz Gonfa Biegna, Dejenie Shiferaw Teklu, Kassu Desta Tullu   +8 more
doaj   +1 more source