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Colistin—A Reappraisal

JAMA, 1963
COLISTIN, a polypeptide antibiotic closely related to polymyxin B, has been in use in the United States for approximately three years. Despite the accumulation of considerable clinical experience with this agent, it is still subject to a good deal of controversy.
Robert G. Petersdorf, James J. Plorde
openaire   +3 more sources

Plasmid-mediated colistin resistance: the final blow to colistin?

International Journal of Antimicrobial Agents, 2016
no ...
Rolain, Jean-Marc   +1 more
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Use of Colistin in Children

Pediatric Infectious Disease Journal, 2009
Colistin, or Polymixin E, is a cationic polypeptide antibiotic obtained from Bacillus spp. It was initially used therapeutically in the United States in 1959 but intravenous formulations were gradually abandoned in the early 1980s due to nephrotoxicity concerns.
Carlton K. K. Lee, Pranita D. Tamma
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Colistin use and colistin resistance in bacteria from animals

International Journal of Antimicrobial Agents, 2016
Colistin has been used in veterinary medicine for decades, mainly for the prevention and treatment of Enterobacteriaceae infections. However, data regarding colistin resistance in bacteria from animals and food of animal origin are relatively scarce, partly because there are methodological difficulties hampering the analysis of susceptibility to ...
Isabelle Kempf   +2 more
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A review on colistin nephrotoxicity

European Journal of Clinical Pharmacology, 2015
Colistin is an antibiotic that was introduced many years ago and was withdrawn because of its nephrotoxicity. Nowadays, reemergence of this antibiotic for multi-drug resistant Gram-negative infections, and a new high dosing regimen recommendation increases concern about its nephrotoxicity. This review attempts to give a view on colistin nephrotoxicity,
Zahra Sahraei   +2 more
openaire   +3 more sources

Intraocular Penetration of Colistin

Archives of Ophthalmology, 1962
Introduction Colistin is a new antibiotic isolated in Japan from the microorganism Aerobacillus colistinus. 1 It is very similar to the polymyxins in its chemical composition, and in its spectrum of activity closely resembles polymyxin B. It is highly inhibitory for many gram-negative organisms and only slightly inhibitory or inactive towards ...
Leonard Apt   +2 more
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Resurgence of colistin use

American Journal of Health-System Pharmacy, 2007
The role of colistin in the treatment of infections caused by multidrug-resistant gram-negative microorganisms is discussed.Colistin is structurally and pharmacologically related to polymyxin B, the other commercially available drug from the polymyxin class. Colistin is bactericidal in nearly all strains of gram-negative bacilli.
Sohini Sarkar   +2 more
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Performance evaluation of colistin rapid NP test for detection of colistin resistance in colistin resistant Enterobacterales

Medical Journal Armed Forces India
Carbapenem-resistant Enterobacterales (CRE) have become a global threat, with colistin being the last resort for treatment. CLSI and EUCAST recommend broth microdilution (BMD) as the reference method for colistin susceptibility testing. Nordmann and Poirel have developed a simple and rapid Polymyxin NP test as an alternative to BMD for screening of ...
Punyatoya Kar   +4 more
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Reviving colistin

Nature Reviews Microbiology, 2023
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