Results 211 to 220 of about 672,024 (402)

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

The aqueous extract of Phellinus igniarius (SH) ameliorates dextran sodium sulfate-induced colitis in C57BL/6 mice

, 2018
Yuqing Sun, Shi Zhong, Jiaqi Yu, Jianxun Zhu, Dong-Feng Ji, Gui-Yan Hu, Chongming Wu, Yougui Li   +7 more
openalex   +2 more sources

Pygopus2 ameliorates mesenteric adipocyte poor differentiation to alleviate Crohn's disease ‐like colitis via the Axin2/GSK3β pathway

, 2022
Jing Li, Lugen Zuo, Zhijun Geng, Qingqing Li, Cheng Yang, Zi Yang, Ruohan Shi, Yueqing Zhou, Wenhu Nie, Yueyue Wang, Xiaofeng Zhang, Sitang Ge, Xue Song, Jianguo Hu   +13 more
openalex   +1 more source

The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma

Chemistry &Biodiversity, EarlyView.
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha, Danielle Twilley, Mona Dawood, Thomas Efferth, Namrita Lall   +4 more
wiley   +1 more source

Close Homolog of L1 Deficiency Exacerbated Intestinal Epithelial Barrier Function in Mouse Model of Dextran Sulfate Sodium-Induced Colitis [PDF]

, 2020
Ying Han, Xiaomeng Wang, Xiang Cheng, Ming Zhao, Tong Zhao, Liang Guo, Dan Liu, Kuiwu Wu, Ming Fan, Ming Shi, Ling‐Ling Zhu   +10 more
openalex   +1 more source

Ig Glycosylation in Ulcerative Colitis: It’s Time for New Biomarkers [PDF]

, 2021
Riccardo Capecchi, Paola Migliorini, Federico Zanzi, S. Maltinti, Ilaria Puxeddu, Nicola de Bortoli, Massimo Bellini, Francesco Costa, Santino Marchi, Lorenzo Bertani   +9 more
openalex   +1 more source

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

Nature Medicine, 2016
B. Lamas, Mathias L. Richard, Valentin Leducq, H. Pham, Marie‐Laure Michel, G. Da Costa, C. Bridonneau, Sarah Jégou, Thomas W. Hoffmann, J. Natividad, L. Brot, S. Taleb, A. Couturier-Maillard, I. Nion‐Larmurier, Fatiha Merabtene, P. Seksik, A. Bourrier, J. Cosnes, B. Ryffel, L. Beaugerie, J. Launay, P. Langella, R. Xavier, H. Sokol   +23 more
semanticscholar   +1 more source

Nutritional Content, Phytochemical Composition, and Physicochemical Properties of Different Quinoa (Chenopodium quinoa Willd.) Seed Varieties

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives Quinoa (Chenopodium quinoa Willd.) is a pseudocereal with documented benefits for human health. The macronutrient composition and phytochemical content of the grain are known to vary depending on the variety and the growing location.
Vassilios Raikos, Shirley De Lima Sampaio, Helen E. Hayes, Gary J. Duncan, Donna Henderson, Nicholas J. Vaughan, Wendy R. Russell, Madalina Neacsu   +7 more
wiley   +1 more source

Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab

Annals of Oncology, 2017
N. Chaput, P. Lepage, C. Coutzac, E. Soularue, K. L. Roux, C. Monot, L. Boselli, É. Routier, L. Cassard, M. Collins, T. Vaysse, L. Marthey, A. Eggermont, V. Asvatourian, E. Lanoy, C. Mateus, C. Robert, F. Carbonnel   +17 more
semanticscholar   +1 more source

Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases

ChemistryEurope, EarlyView.
Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang, Jinxia Wang, Guang‐Zhi Jin, István Bányai, Dzmitry Shcharbin, Ivan Stoikov, Mingwu Shen, Xiangyang Shi   +7 more
wiley   +1 more source