Results 211 to 220 of about 302,337 (268)

Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease

Journal of Periodontology, EarlyView.
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar, Jeba Mercy Gnanasekaran, Niyant Ganesh, Cindy Zhou, Amy Plotkin, Giacomo Baima, Massimo Costalonga, Fenfen Zhou, Hanping Feng, Priyam Jani, Jean‐Pierre Raufman, Vivek Thumbigere‐Math   +11 more
wiley   +1 more source

Virus-derived serpin reduces immuno-coagulopathic damage in murine colitis by targeting the urokinase-type plasminogen activator receptor (uPAR) and complement. [PDF]

Sci Rep
Lucas AR, Monder H, Enow J, Woodrow C, Spaccarelli L, Garg A, Schlievert J, Elmadbouly N, Dupati A, Aliskevich E, Saju R, Kilbourne J, Lowe K, Hamada M, Pinteric A, Zanetti IR, Satyanarayanan RS, Gisriel S, Florsheim EB, Rahman M, Irving J, McFadden G, Kong W, Zhang L.   +23 more
europepmc   +1 more source

Immune-Mediated Thrombocytopenia in an Ulcerative Colitis Patient After Initiating Filgotinib Treatment: A Case Report. [PDF]

Clin Case Rep
van der Hoff MJ, El-Morabit F, Löwenberg M.   +2 more
europepmc   +1 more source

Neuroprotective Potential of Mesenchymal Stem Cell-Based Therapy in Acute Stages of TNBS-Induced Colitis in Guinea-Pigs

, 2015
Ainsley M. Robinson, Sarah Miller, Natalie L. Payne, Richard L. Boyd, Samy Sakkal, Kulmira Nurgali   +5 more
openalex   +2 more sources

Reshaping study design for faster extrapolation‐based drug approval in pediatric inflammatory bowel diseases: An ESPGHAN–NASPGHAN position paper

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Children with inflammatory bowel diseases (IBD) have limited access to the available advanced therapies, given the lengthy gap between adult and pediatric approval. We aimed to review key hurdles for pediatric trials and recommend practical solutions.
Dan Turner, Amit Assa, Mikkel Malham, Shira Yuval Bar‐Asher, Carla Rayan, Jeffrey S. Hyams, Holm H. Uhlig, Brad Pasternak, David C. Wilson, Hilary K. Michel, Lissy de Ridder, Eric Zuckerman, Marina Aloi, Peter Szitanyi, Marla C. Dubinsky, Anne M. Griffiths, Roberto Saldana, Javier Martín‐de‐Carpi, Eytan Wine, Richard K. Russell, Jeremy Adler, Joseph Picoraro   +21 more
wiley   +1 more source

Vedolizumab for extraintestinal manifestations in pediatric inflammatory bowel disease: Results from the VedoKids study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Extraintestinal manifestations (EIMs) manifest in 6%‐47% of patients with inflammatory bowel disease (IBD). Here, we characterize the course of EIMs in pediatric patients receiving vedolizumab included in the VedoKids cohort study. This was a subgroup analysis of the pediatric VedoKids cohort, a multicenter, prospective study of children (aged
Giulia D'Arcangelo, Dan Turner, Oren Ledder, Esther Orlanski‐Meyer, Efrat Broide, Maya Granot, Manar Matar, Seamus Hussey, Anat Yerushalmy‐Feler, Christoph Norden, Erasmo Miele, Marina Aloi   +11 more
wiley   +1 more source

Periodontitis salivary microbiota exacerbates colitis by CXCL3 derived from gut microbiota-induced macrophages. [PDF]

Microbiome
Qian J, Tao Q, Shen Y, Wang L, Wang M, Wang N, Liang Q, Lu J, Huang Y, Liao W, Chen R, Ge R, Yuan Z, Li Y, Shen H, Gao Q, Yan F.   +16 more
europepmc   +1 more source

Colitis Associated with Clostridium difficile in Specific-Pathogen-Free C3H-scid Mice

, 2007
Kawano Akihiro, Manabu Ikeda, Iritani Riichirou, Kinoshita Akiko, Kaori Watanabe, Hayao Tatsuo, Toshiaki Kokubo, Satoru Matsushita   +7 more
openalex   +2 more sources

Anti‐tumor necrosis factor‐α monotherapy versus combo therapy with immunosuppressant in pediatric inflammatory bowel disease: A real‐life study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives The aim of the study is to evaluate the efficacy of anti‐tumor necrosis factor (TNF)‐α monotherapy versus combination anti‐TNF‐α and immunosuppressive therapy. Methods A single‐center, retrospective, observational study was conducted on inflammatory bowel disease (IBD) children.
Flora Fedele, Massimo Martinelli, Caterina Strisciuglio, Elena Scarpato, Annamaria Staiano, Erasmo Miele   +5 more
wiley   +1 more source

CV-SCAN (Crystal Violet Staining for Colitis-Associated Neoplasia): A Novel Endoscopic Staining Method to Detect Paneth Cell Metaplasia and Ulcerative Colitis (UC)-Associated Neoplasia in UC. [PDF]

Dig Endosc
Tomioka A, Chiya N, Kurihara C, Okada Y, Narimatsu K, Higashiyama M, Komoto S, Hokari R.   +7 more
europepmc   +1 more source