Results 321 to 330 of about 672,024 (402)

Whole microbiota transplantation restores gut homeostasis throughout the gastrointestinal tract

open access: yesiMeta, EarlyView.
This study introduces whole microbiota transplantation (WMT), a synergistic therapeutic approach that concurrently transplants small intestinal and fecal microbiota. In germ‐free mice, WMT outperforms conventional fecal microbiota transplantation (FMT) in restoring gut microbiota diversity and abundance.
Bufu Tang   +8 more
wiley   +1 more source

Bubble Trouble: Portal Venous Gas Embolism Following Hydrogen Peroxide Enema. [PDF]

open access: yesACG Case Rep J
Mann P   +5 more
europepmc   +1 more source

Genome‐wide CRISPR screen reveals an uncharacterized spliceosome regulator as new candidate immunotherapy target

open access: yesiMeta, EarlyView.
This study identifies the uncharacterized gene C9ORF50 as a novel regulator of immune evasion. Functioning as an intrinsically disordered protein, C9ORF50 drives liquid‐liquid phase separation to facilitate spliceosome assembly and maintain RNA splicing fidelity.
Tong Shao   +24 more
wiley   +1 more source

Palbociclib-Induced Apoptotic Colopathy: A Case Report and Review of the Literature. [PDF]

open access: yesEur J Case Rep Intern Med
Díaz-Couselo FA   +5 more
europepmc   +1 more source

The Role of Viral and Bacterial Infections in the Etiology of Behçet's Disease

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Bacterial and viral pathogens may play a key role in Behçet's disease (BD) pathogenesis by triggering autoimmunity, molecular mimicry, or microbiome disruption. These infectious agents could initiate inflammatory pathways, contributing to BD's diverse clinical manifestations.
Mohsen Moghoofei   +4 more
wiley   +1 more source

Clinical and Biochemical Factors Associated With Infliximab Pharmacokinetics in Adult Patients With Inflammatory Bowel Disease

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Many patients with inflammatory bowel disease (IBD) do not adequately respond to infliximab, potentially due to individual differences in pharmacokinetics (PK). This study aimed to identify clinical and biochemical variables associated with infliximab PK.
Ilse A. Pool   +6 more
wiley   +1 more source

Accuracy of Bowel Ultrasound for Detecting Inflammatory Bowel Disease at a Tertiary Hospital in Central South Africa

open access: yesJournal of Clinical Ultrasound, EarlyView.
Bowel wall thickness, as measured by bowel ultrasound, demonstrates high diagnostic accuracy in evaluating patients with suspected inflammatory bowel disease (IBD). When combined with other bowel ultrasound parameters, this non‐invasive tool can serve as an effective screening method to accelerate IBD diagnosis.
Amanda Hendricks, Henra Muller
wiley   +1 more source

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