Results 41 to 50 of about 2,917,787 (333)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Collaborative Approaches to Addressing Domestic and Sexual Violence among Black and Minority Ethnic Communities in Southampton: A Case Study of Yellow Door

Societies, 2022
Domestic and sexual abuse have been in the academic discourse for quite some time. In recent years in the United Kingdom, the government, non-governmental organisations (NGOs) and the charity sector have doubled their efforts to tackle this challenge ...
Oluwatayo Adeola Olabanji
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Historical Collaborative Geocoding

ISPRS International Journal of Geo-Information, 2018
The latest developments in the field of digital humanities have increasingly enabled the construction of large data sets which can be easily accessed and used.
Rémi Cura, Bertrand Dumenieu, Nathalie Abadie, Benoit Costes, Julien Perret, Maurizio Gribaudi   +5 more
doaj   +1 more source

The $746 Million A Year School-to-Prison Pipeline: The Ineffective, Discriminatory, and Costly Process of Criminalizing New York City Students [PDF]

, 2017
This report, released by the Center for Popular Democracy and Urban Youth Collaborative, reveals the staggering yearly economic impact of the school-to-prison pipeline in New York City, $746.8 million.
Center for Popular Democracy, Urban Youth Collaborative   +1 more
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

A Collaborative Data Network for the Asia Oceania Region Enabled by Emerging Technologies to Foster Innovation in a Secure and Open Environment

Data Science Journal
A discoverable inventory of items of value and importance to a community, country, or region has many benefits. These benefits can be for reporting (state of the environment, achievement of Sustainable Development Goals, conservation objectives), for ...
Alison Specht, Kim Bryceson, Shoufeng Cao, Margaret O’Brien, S. M. Guru, Pedro Pizzigatti Correa, Michelle Waycott   +6 more
doaj   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

Collaborative trails in e-learning environments [PDF]

, 2004
This deliverable focuses on collaboration within groups of learners, and hence collaborative trails. We begin by reviewing the theoretical background to collaborative learning and looking at the kinds of support that computers can give to groups of ...
Bodnar, E., Brasher, A., de Freitas, Sara, Emans, B., Eyssautier, C., Jones, A., Keenoy, K., Levene, Mark, Montandon, L., Pernin, J.P., Schoonenboom, J., Turcsanyi-Szabo, M., Waycott, J.   +12 more
core  

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source