Results 71 to 80 of about 634,428 (265)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Design Thinking and Collaborative Learning [PDF]
, 2014 This paper presents design thinking as an alternative approach to conduct research on collaborative learning with technology. The underlying premise of the paper is the need to adopt human-centered design principles in research and design of computer ...
Durall-Gazulla, Eva +2 more
core +1 more source
Collaborative Procrastination.
, 2020 The problem of inconsistent planning in decision making, which leads to undesirable effects such as procrastination, has been studied in the behavioral-economics literature, and more recently in the context of computational behavioral models. Individuals, however, do not function in isolation, and successful projects most often rely on team work.
Aris Anagnostopoulos +2 more
openaire +5 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
A Metrics Approach for Collaborative Systems [PDF]
This article presents different types of collaborative systems, their structure and classification. This paper defines the concept of virtual campus as a collaborative system.
Cristian CIUREA
core
RoboticsThe inspection of sewer pipes in the UK is costly, and if not inspected regularly, they are costly and disruptive to repair. This paper presents the Mega-Joey, a novel miniature, tether-less robot platform that is capable of autonomously navigating and ...
Hitesh Bhardwaj +10 more
doaj +1 more source
To collaborate or not to collaborate: understanding human-robot collaboration
2022 IEEE 18th International Conference on Automation Science and Engineering (CASE), 2022 Villani, Valeria +4 more
openaire +2 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Collaborative Educational Systems [PDF]
This paper starts describing the key concepts of collaborative systems and the impact of this to educational systems. There are presented the main properties and quality characteristics for the collaborative educational systems.
Cristian CIUREA, Rodica BÃTÃGAN
core
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source