Results 71 to 80 of about 5,304,485 (254)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Defining Carers [PDF]

open access: yes, 2015
The purpose of this paper is less to answer questions than to ask them, and less to define ‘carers’ than to understand who they are. In particular, its purpose is to ask why the label ‘family carer’ may be rejected by some of them, or by particular ...
Care Alliance Ireland
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Integrating care for people with depression: developments in the Netherlands

open access: yesInternational Journal of Integrated Care, 2010
Introduction: In this article we describe the history and present state of integrated care for people with depression in the Netherlands. The central question is: what are the developments in integrated care for people with depression in the Netherlands ...
Adri H. Peters   +2 more
doaj  

Collaborative Cardiac Care

open access: yesJACC: Case Reports, 2019
Left main artery coronary disease represents the highest risk lesion of ischemic heart disease. Revascularization can be accomplished by surgery or percutaneous interventions.
Rohan Mehta, MD   +3 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Key characteristics of collaborative care.

open access: yes, 2014
Key characteristics of collaborative care.
Joanna L. Hudson (636026)   +10 more
core   +1 more source

Acute care needs in a rural Sub-Saharan African Emergency Centre: A retrospective analysis

open access: yesAfrican Journal of Emergency Medicine, 2012
Introduction: In June of 2008, Karoli Lwanga (“Nyakibale”) Hospital and Global Emergency Care Collaborative (GECC) opened the first functional Emergency Centre (EC) in rural Uganda.
Usha Periyanayagam   +7 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

A Framework for collaborative writing with recording and post-meeting retrieval capabilities [PDF]

open access: yes, 2004
From a HCI perspective, elucidating and supporting the context in which collaboration takes place is key to implementing successful collaborative systems.
King, David   +3 more
core   +1 more source

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