Results 41 to 50 of about 47,670 (249)

Spatiotemporal Dynamics and Drivers of Ecosystem Service Value in Coastal China, 1980–2020

Land
In response to the widespread decline in ecosystem service value (ESV) caused by rapid industrialization and urbanization-driven land-use transitions in Coastal China—characterized by shrinking farmland and expanding built-up land and crystallized in the
Qing Liu, Jiajun Huang, Xingchuan Gao, Yufan Chen, Xinyi Shao, Pengtao Wang   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

How Should the Effectiveness of Marine Functional Zoning in China Be Evaluated? Taking Wenzhou Marine Functional Zoning as an Example

Land, 2022
Marine functional zoning is a basic form of marine management proposed and organized by the Chinese government in the late 1980s, and the third round of planning and implementation has been completed.
Renfeng Ma, Jiarui Chen, Qi Pan, Yuxian Cheng, Weiqin Wang, Baoyu Zhu, Jingwu Ma, Jiaming Li   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Collaborative Governance

EDUCATION AND INDUSTRY REVIEW
Collaborative governance strengthens public administration by fostering partnerships among government, communities, civil society, and other stakeholders to address complex societal challenges through shared decision-making and accountability. By promoting inclusive participation, collaborative leadership, and digital engagement, it enhances public ...
  +4 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Association of prenatal and childhood environment smoking exposure with puberty timing: a systematic review and meta-analysis

Environmental Health and Preventive Medicine, 2018
Objectives Mothers who smoke during pregnancy or while their children are small were common in some populations. Epidemiological studies have tried to detect the effect of prenatal tobacco smoke (PTS), and childhood environmental tobacco smoke (ETS) on ...
Yiwen Chen, Qin Liu, Wenyan Li, Xu Deng, Bo Yang, Xin Huang   +5 more
doaj   +1 more source

The association between sleep duration, bedtimes, and early pubertal timing among Chinese adolescents: a cross-sectional study

Environmental Health and Preventive Medicine, 2020
Background and objective Early pubertal timing is associated with sleep among Western adolescents, but little is known about this association in Chinese adolescents, especially with regard to the association between bedtimes and early pubertal timing ...
Hua Diao, Hong Wang, Lianjian Yang, Ting Li   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source