Results 81 to 90 of about 129,919 (293)

Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin. [PDF]

, 2017
The small leucine-rich proteoglycans (SLRPs) are important regulators of extracellular matrix assembly and cell signalling. We have determined crystal structures at ~2.2Å resolution of human fibromodulin and chondroadherin, two collagen-binding SLRPs ...
Bihan, Dominique, Bonna, Arkadiusz, Farndale, Richard W, Hohenester, Erhard, Kalamajski, Sebastian, Paracuellos, Patricia   +5 more
core   +1 more source

Raman Microscopy at the Organic–Inorganic Interfaces in Human Calcified Aortic Valves Shows the Co‐Existence of Whitlockite Crystals and Carbonated Hydroxyapatite‐Mineralized Collagen Fibrils

Advanced Functional Materials, EarlyView.
This study advances our understanding of aortic valve stenosis by capturing spatially resolved chemical and structural changes at the nanoscale. The findings highlight the potential of combined Raman and electron microscopy for understanding calcification mechanisms across diverse tissue types.
Robin H. M. Van der Meijden, Carolien T. A Kuster, Amber van Broekhoven, Raphaela Allgayer, Luco Rutten, Rona Roverts, Marta Cerruti, Elena Macías‐Sánchez, Jan Hein Cornel, Salloua el Messaoudi, Anat Akiva, Nico Sommerdijk   +11 more
wiley   +1 more source

Mechanical properties and collagen cross-linking of the patellar tendon in old and young men [PDF]

, 2009
Udgivelsesdato: 2009-Jun-25Age-related loss in muscle mass and strength impairs daily life function in the elderly. However, it remains unknown if tendon properties also deteriorate with age.
Aagaard, Per, Couppe, Christian, Hansen, Philip, Kjaer, Michael, Kongsgaard, Mads, Kovanen, Vuokko, Magnusson, S Peter, Suetta, Charlotte   +7 more
core   +1 more source

Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype

Advanced Functional Materials, EarlyView.
In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He, Wang Sik Lee, Phattadon Yajan, Aaron Lee, Mauro Sousa de Almeida, Sandeep Keshavan, Jozef Adamcik, Céline Loussert‐Fonta, Dimitri Vanhecke, Barbara Rothen‐Rutishauser, Alke Petri‐Fink   +10 more
wiley   +1 more source

Remodeling by fibroblasts alters the rate-dependent mechanical properties of collagen [PDF]

, 2016
The ways that fibroblasts remodel their environment are central to wound healing, development of musculoskeletal tissues, and progression of pathologies such as fibrosis.
Babaei, B., Davarian, A., Elson, E.L., Genin, G.M., Lee, S.-L., McConnaughey, W.B., Pryse, K.M.   +6 more
core   +1 more source

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

Advanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco, Pierfrancesco Gaziano, Serena Anglese, Simone Morganti, Carlo de Vincentiis, Ferdinando Auricchio, Michele Marino, Michele Conti   +7 more
wiley   +1 more source

Effect of an aqueous extract of Phaseolus vulgaris on the properties of tail tendon collagen of rats with streptozotocin-induced diabetes

Brazilian Journal of Medical and Biological Research, 2003
Changes in the structural and functional properties of collagen caused by advanced glycation might be of importance for the etiology of late complications in diabetes.
L. Pari, S. Venkateswaran
doaj   +1 more source

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

Advanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez, Mulazim Hussain Asim, Shumaila Arshad, Gergely Kali, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Stability of cross-linked collagen [PDF]

, 2010
Teoretická část této bakalářské práce pojednává o obecných vlastnostech kolagenu, který je nejčastěji rozšířeným vláknitým proteinem v těle, o síťování kolagenu, které vede ke zlepšení mechanických i chemických vlastností, a o široce využívaných ...
Součková, Gabriela
core  

The pathogenesis of tendinopathy. A molecular perspective [PDF]

, 2004
There are many publications that discuss the aetiology, diagnosis and treatment of the various forms of tendinopathy, but few are based on conclusive scientific evidence.
Riley, GP
core   +1 more source