Results 81 to 90 of about 4,668,535 (288)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Collagen Cross-linking in Keratoconus Patients with Thin Corneas: Short-Term Results

, 2012
Pur po se: To study the effectiveness and safety of corneal collagen cross-linking with hypoosmolar riboflavin solution applied to keratoconus patients with thin corneas.
Nurullah Çağıl, Nagihan Uğurlu, Hasan Basri Çakmak, Uǧurlu, Nagihan, Turak, Derviş, Çakmak, Hasan Basri, ÇAĞIL, NURULLAH, Şimşek, Şaban, Kocam̈ş, Sucattin Ilker   +8 more
core   +1 more source

Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces

Advanced Functional Materials, EarlyView.
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng, TzuChun Chung, Katpady Akhil Tantry, Siyu Wu, Jing Tian, Yunqi Cui, Lanyu Li, Yongzan Zhou, Zhilei Zhang, Zhe Su, Gaili Cao, Kun‐Wei Yeh, Ruipeng Li, Xianghui Xiao, Adam F. G. Leontowich, Yuan‐Yu Hsueh, Zhao Pan, Kam C. Tam, Badri Narayanan, Song Li, Yimin. A. Wu   +20 more
wiley   +1 more source

Simultaneous versus sequential photorefractive keratectomy and cross-linking for the management of early keratoconus

Delta Journal of Ophthalmology, 2016
Purpose The aim of this study was to compare the safety and efficacy of simultaneous topography-guided photorefractive keratectomy (PRK) and corneal collagen cross-linking (CXL) with consecutive topography-guided PRK and CXL. Patients and methods A total
Ashraf Bor′i
doaj   +1 more source

Guanosine‐Quadruplex Hydrogels as Dynamic, Mechanically Tunable and Ion Conductive 3D Scaffolds for Cell Culture Applications

Advanced Functional Materials, EarlyView.
Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur, Minye Jin, Pavel Milkin, Deepa Negi, Carla Cofiño Fabres, Hubert Gojzewski, Leonid Ionov, Alla Synytska, Andries van der Meer, Robert Passier, Julieta I. Paez   +10 more
wiley   +1 more source

In Situ Interfacial Assembly of Dynamic Semi‐Interpenetrating Biopolymer Networks for Robust and Mechanically Adaptive Droplet Interfaces

Advanced Functional Materials, EarlyView.
A dynamic interfacial semi‐interpenetrating polymer network is constructed by sequential assembly of β‐sheet‐rich SF and CS‐RL. The SF framework provides mechanical strength, while dynamically associated CS‐RL enables local rearrangement, allowing droplets to rapidly reconfigure without loss of interfacial integrity.
Yaping Zhang, Yujie Liu, Yikai Xu, Xunda Feng, Ling Zhang, Hongbo Zeng, Hao Liu, Xiaohui Mao   +7 more
wiley   +1 more source

Corneal Collagen Cross-Linking

, 2013
The first comprehensive textbook on corneal collagen-cross ...
Hafezi, Farhad (Ed.), Bradley, J. (Ed.)
core  

The process of EDC-NHS Cross-linking of reconstituted collagen fibres increases collagen fibrillar order and alignment. [PDF]

, 2014
We describe the production of collagen fibre bundles through a multi-strand, semi-continuous extrusion process. Cross-linking using an EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide), NHS (N-hydroxysuccinimide) combination was considered.
J. H. Shepherd, R. E. Cameron, D. V. Shepherd, S. M. Best, S. J. Kew, S. Ghose   +5 more
core   +2 more sources

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source

TGFbeta Cross-linked to Microcarriers as Injectable IVD Therapy in Dogs and Humans

Global Spine Journal, 2016
Introduction Studies designed to use large canine models and translate the results to human practice must take into account the ex vivo and in vitro differences in the bone marrow derived stem cells(MSCs) and their response to a covalently bound growth ...
Alessandro Bertolo, Frank Steffen, Fanny Arcolino, Simona Capossela, Anna Rita Taddei, Martin Baur, Tobias Poetzel, Jivko Stoyanov   +7 more
doaj   +1 more source