Results 31 to 40 of about 437,388 (294)

Mechanical behavior of osteoporotic bone at sub-lamellar length scales [PDF]

, 2015
Osteoporosis is a disease known to promote bone fragility but the effect on the mechanical properties of bone material, which is independent of geometric effects, is particularly unclear.
Anna eShipov, Asa eBarber, Asa eBarber, Ines eJimenez-Palomar, Ron eShahar   +4 more
core   +2 more sources

Nonenzymatic Glycosylation Products on Collagen Covalently Trap Low-Density Lipoprotein [PDF]

Diabetes, 1985
Advanced nonenzymatic glycosylation products capable of cross-linking proteins accumulate on collagen in vivo in proportion to time-averaged blood glucose concentration. In this report, we have evaluated the ability of advanced nonenzymatic glycosylation productsformed on collagen in vitro to covalently bind low-density lipoprotein (LDL) in a manner ...
M, Brownlee, H, Vlassara, A, Cerami
openaire   +2 more sources

Structure-mechanics relationships of collagen fibrils in the Osteogenesis Imperfecta Mouse model [PDF]

, 2015
The collagen molecule, which is the building block of collagen fibrils, is a triple helix of two α1(I) chains and one α2(I) chain. However, in the severe mouse model of osteogenesis imperfecta (OIM), deletion of the COL1A2 gene results in the ...
Andriotis, OG, Buhler, MJ, Chang, SW, Davies, DE, Howarth, PH, Shefelbine, S, Thurner, PJ, Vanleene, M   +7 more
core   +4 more sources

The effects of shark liver oil on fibroblasts and collagen density in the periodontal ligaments of Wistar rats induced with Porphyromonas gingivalis

Dental Journal, 2019
Background: Periodontitis is an infection in tooth-supporting tissues caused by a specific microorganism, Porphyromonas Gingivalis (PG), which can trigger collagen destruction.
Dian Mulawarmanti, Dwi Andriani, Dian Widya Damaiyanti, Farizia Putri Khoirunnisa, Alifati Nita Juliatin   +4 more
doaj   +1 more source

Alginate Conjugation Increases Toughness in Auricular Chondrocyte Seeded Collagen Hydrogels

Bioengineering, 2023
Current auricular cartilage replacements for pediatric microtia fail to address the need for long-term integration and neocartilage formation. While collagen hydrogels have been successful in fostering neocartilage formation, the toughness and ...
Leigh Slyker, Lawrence J. Bonassar
doaj   +1 more source

Preconditioning of mesenchymal stromal cells with low-intensity ultrasound: influence on chondrogenesis and directed SOX9 signaling pathways [PDF]

, 2020
Background: Continuous low-intensity ultrasound (cLIUS) facilitates the chondrogenic differentiation of human mesenchymal stromal cells (MSCs) in the absence of exogenously added transforming growth factor-beta (TGFβ) by upregulating the expression of ...
A Argentaro, A Augello, A Katsumi, A Woods, A Woods, AD Miller, AH Huang, B Yang, BH Choi, C Huang, C Matta, CA Simmons, CB Little, CJ O’Conor, CY Huang, D Schumann, DR Haudenschild, EM Darling, F Dell'Accio, G Coricor, H Sim, H-C Hsu, HJ Kwon, HJ Lee, HJ Lee, J Li, J Puetzer, JC Sng, JD Kisiday, JH Cui, JH Cui, JW Choi, K Ebisawa, K Pelttari, L Bian, Li Ling, LJ Ng, M Shakibaei, M Tsuda, MA Corrigan, MB Mueller, N Fahy, N Thelin, NP Whitney, P Müller, R Ogawa, RL Mauck, RM Delaine-Smith, RS Tigli, S Murakami, S Noriega, S Noriega, S Yamaguchi, SD Cook, SD Cook, T Furumatsu, T Guo, T Ito, T Juhasz, T Nishida, T Sanjukta Guha, TM Louw, V Lefebvre, V Lefebvre, W Huang, W Huang, Z Li, ZJ Zhang   +67 more
core   +2 more sources

COX-2 modulates mammary tumor progression in response to collagen density. [PDF]

Breast Cancer Res, 2016
High breast density is linked to an increased risk of breast cancer, and correlates with changes in collagen. In a mouse model of mammary carcinoma in the context of increased collagen deposition, the MMTV-PyMT/Col1a1 (tm1jae) , there is accelerated mammary tumor formation and progression.
Esbona K, Inman D, Saha S, Jeffery J, Schedin P, Wilke L, Keely P.   +6 more
europepmc   +4 more sources

Computational modeling of acute myocardial infarction [PDF]

, 2016
This is an Accepted Manuscript of an article published by Taylor & Francis Group in Computer Methods in Biomechanics and Biomedical Engineering on October, 2016, available online at: http://www.tandfonline.com/10.1080/10255842.2015.1105965Myocardial ...
Kuhl, E., Sáez Viñas, Pablo
core   +2 more sources

Low Density Lipoproteins Modulate Collagen Metabolism in Fibroblasts

Journal of Cardiovascular Pharmacology and Therapeutics, 2003
High levels of low-density lipoprotein are associated with atherosclerosis, and myocardial and arterial remodeling. We postulated that low-density lipoprotein influences collagen synthesis and degradation in fibroblasts as a potential mechanism of tissue remodeling.
Jacob, Joseph, Subramanian, Ranganathan, Jawahar L, Mehta   +2 more
openaire   +2 more sources

Tissue engineering a fetal membrane [PDF]

, 2011
The aim of this study was to construct an artificial fetal membrane (FM) by combination of human amniotic epithelial stem cells (hAESCs) and a mechanically enhanced collagen scaffold containing encapsulated human amniotic stromal fibroblasts (hASFs ...
Adam M. Squires, Anna L. David, Bipasha Chowdhury, Che John Connon, Connon C.J., Grinnell F., Ian William Hamley, Jones R.R., Kirkham S.M., Roanne Razalia Jones, Shengli Mi, Trinkaus R.V.   +11 more
core   +1 more source