Results 1 to 10 of about 600,628 (357)

Evolutionary Patterns of Collagen Fiber Arrangement and Calcification in Atherosclerosis [PDF]

Research
Collagen is a major structural component of human tissues, and its spatial arrangement is critical for maintaining tissue mechanical integrity and regulating cell behavior. In atherosclerosis (AS), collagen fiber arrangement has been implicated in plaque
Chunyang Ma, Zhenzhen Jia, Shuaiyin Liu, Xiangyi Liao, Hongyan Kang, Xufeng Niu, Yubo Fan   +6 more
doaj   +2 more sources

Pathological and immunological differences of arterial thrombi and wall caused by three different periodontal bacterial injections in rat models and proposals on the pathogeneses of vascular diseases

Clinical and Experimental Dental Research, 2021
Objectives Periodontal bacteria that have been studied show a strong connection to various vascular diseases. Among the many kinds of periodontal bacteria, Porphyromonas gingivalis (Pg) is well examined in the general aspects and in a rat model. However,
Takehisa Iwai, Yoshiki Matsui, Kaori Homma, Tamiko Takemura, Mutsunori Fujiwara, Norio Aoyama, Asuka Furukawa, Hiroki Sato, Yuichi Izumi   +8 more
doaj   +1 more source

Therapeutic Strategy for Patients with Concomitant Pulmonary Artery Hypertension and Hypertrophic Obstructive Cardiomyopathy: A Rare Case Report

Medicina, 2023
Combined cases of hypertrophic obstructive cardiomyopathy (HOCM) and pulmonary arterial hypertension (PAH) are rare and have a management dilemma. Although preload is crucial in the management of HOCM, anti-PAH agents dramatically change the preload ...
Toshihide Izumida, Teruhiko Imamura, Shuhei Tanaka, Shuji Joho, Koichiro Kinugawa   +4 more
doaj   +1 more source

Tofacitinib versus tocilizumab in the treatment of biological-naïve or previous biological-failure patients with methotrexate-refractory active rheumatoid arthritis

RMD Open, 2021
Objectives To compare effectiveness between tofacitinib and tocilizumab treatments for biological disease-modifying antirheumatic drug (bDMARD)-naïve patients or previous bDMARD-failure patients with active rheumatoid arthritis (RA) refractory to ...
Yukitaka Ueki, Yukitomo Urata, Shunsuke Mori, Tamami Yoshitama   +3 more
doaj   +1 more source

A severe case of thrombocytopenia, anasarca, fever, renal insufficiency or reticulin fibrosis, and organomegaly syndrome with myocardial and skeletal muscle calcification despite hypocalcemia: a case report

Journal of Medical Case Reports, 2021
Background TAFRO (thrombocytopenia, anasarca, fever, renal insufficiency or reticulin fibrosis, and organomegaly) syndrome is a recently recognized disease with a variety of presentations of variable severity.
Shogo Minomo, Yu Fujiwara, Shota Sakashita, Akito Takamura, Kaoru Nagata   +4 more
doaj   +1 more source

Role of Collagen in Airway Mechanics

Bioengineering, 2021
Collagen is the most abundant airway extracellular matrix component and is the primary determinant of mechanical airway properties. Abnormal airway collagen deposition is associated with the pathogenesis and progression of airway disease.
Lumei Liu, Brooke Stephens, Maxwell Bergman, Anne May, Tendy Chiang   +4 more
doaj   +1 more source

Contribution of collagen XIII to lung function and development of pulmonary fibrosis

BMJ Open Respiratory Research, 2023
Background Collagen XIII is a transmembrane collagen associated with neuromuscular junction development, and in humans its deficiency results in congenital myasthenic syndrome type 19 (CMS19), which leads to breathing difficulties. CMS19 patients usually
Riitta Kaarteenaho, Oula Norman, Jarkko Koivunen, Antti M Salo, Joni M Mäki, Johanna Myllyharju, Taina Pihlajaniemi, Anne Heikkinen   +7 more
doaj   +1 more source

Collagen Biosynthesis, Processing, and Maturation in Lung Ageing

Frontiers in Medicine, 2021
In addition to providing a macromolecular scaffold, the extracellular matrix (ECM) is a critical regulator of cell function by virtue of specific physical, biochemical, and mechanical properties.
Ceylan Onursal, Elisabeth Dick, Ilias Angelidis, Herbert B. Schiller, Claudia A. Staab-Weijnitz   +4 more
doaj   +1 more source

The first case of thrombocytopenia, anasarca, fever, renal impairment or reticulin fibrosis, and organomegaly (TAFRO) syndrome with unilateral adrenal necrosis: a case report

Journal of Medical Case Reports, 2018
Background TAFRO syndrome, which was first reported in 2010 in Japan, is a relatively rare disease characterized by thrombocytopenia, anasarca, fever, renal impairment, reticulin fibrosis, and organomegaly.
Yu Fujiwara, Kanae Ito, Akito Takamura, Kaoru Nagata   +3 more
doaj   +1 more source

Organization and collagen volume density of the gingiva in the patients with periodontitis [PDF]

Praxis Medica, 2015
Collagen is a major constituent of the gingival extracellular matrix, which crucially affects the histoarchitecture of the gingival tissue. Collagen type I dominates the gingival tissue, while type II, III and IV are present to a lesser extent.
Marjanović D., Šehalić M., Kujundžić B., Stamatović D., Arsić Z., Đorđević N.   +5 more
doaj   +1 more source