Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan +13 more
wiley +1 more source
Matrix Biology Plus, 2019 High conservation of extracellular matrix proteins often makes the generation of potent species-specific antibodies challenging. For collagen VII there is a particular preclinical interest in the ability to discriminate between human and murine collagen ...
Olivier Bornert +6 more
doaj
Clinical observation on collagen disease as vasculitis, including current 4 cases
, 1976 Takehide Takuma, Nobuhiro Sugino
openalex +2 more sources
Relationship between serum and hepatic 7S fragments of type IV collagen in chronic liver disease [PDF]
, 1996 Takeaki Suou +4 more
openalex +1 more source
Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa +5 more
wiley +1 more source
New lethal disease involving type I and III collagen defect resembling geroderma osteodysplastica, De Barsy syndrome, and Ehlers-Danlos syndrome IV. [PDF]
, 1998 Arja Jukkola +6 more
openalex +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
Advanced Healthcare Materials, EarlyView.What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell +5 more
wiley +1 more source
Constant and cyclic shear stress regulate collagen fibers self-assembly
Medicine in Novel Technology and DevicesCollagen fibers are a key structural component in the plaques of atherosclerosis (AS), playing a vital role in regulating plaque stability. Investigating the factors that affect collagen fiber self-assembly and their mechanisms not only aid in assessing ...
Chunyang Ma +5 more
doaj
MT1-MMP-Deficient Mice Develop Dwarfism, Osteopenia, Arthritis, and Connective Tissue Disease due to Inadequate Collagen Turnover [PDF]
, 1999 Kenn Holmbeck +11 more
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Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee +10 more
wiley +1 more source