Results 11 to 20 of about 10,231,394 (364)
The use of urinary proteomics in the assessment of suitability of mouse models for ageing [PDF]
, 2017 Ageing is a complex process characterised by a systemic and progressive deterioration of biological functions. As ageing is associated with an increased prevalence of age-related chronic disorders, understanding its underlying molecular mechanisms can ...
Bajwa, Seerat +17 more
core +7 more sources
Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. [PDF]
, 2016 Cytochrome P450 (CYP) monooxygenases epoxidize the omega-3 polyunsaturated fatty acid (PUFA) docosahexaenoic acid into novel epoxydocosapentaenoic acids (EDPs) that have multiple biological actions.
Hammock, Bruce D +5 more
core +6 more sources
Collagen Biosynthesis, Processing, and Maturation in Lung Ageing
Frontiers in Medicine, 2021 In addition to providing a macromolecular scaffold, the extracellular matrix (ECM) is a critical regulator of cell function by virtue of specific physical, biochemical, and mechanical properties.
Ceylan Onursal +4 more
doaj +1 more source
BMC Immunology, 2013 BackgroundInterstitial lung disease (ILD) is frequently associated with collagen diseases. The prognosis of acute-onset diffuse ILD (AoDILD) occurring in collagen disease patients is very poor.
S. Oka +6 more
semanticscholar +1 more source
ADAM15 modulates outside-in signalling in chondrocyte–matrix interactions [PDF]
, 2008 ADAM15 belongs to a family of transmembrane multi-domain proteins implicated in proteolysis, cell–cell and cell–matrix interactions in various disease conditions.
Burkhardt, Harald +2 more
core +1 more source
Organization and collagen volume density of the gingiva in the patients with periodontitis [PDF]
Praxis Medica, 2015 Collagen is a major constituent of the gingival extracellular matrix, which crucially affects the histoarchitecture of the gingival tissue. Collagen type I dominates the gingival tissue, while type II, III and IV are present to a lesser extent.
Marjanović D. +5 more
doaj +1 more source
The Journal of the International Society of Physical and Rehabilitation Medicine, 2019 Purpose: In elderly patients with collagen disease, walking ability tends to decrease due to treatment with corticosteroids and long-term hospitalization.
Shinya Yamauchi +4 more
doaj +1 more source
Non-Infectious Scleritis and Systemic Collagen Vascular Disease Association
Siriraj Medical Journal, 2020 Objective: To evaluate scleritis type in association with a systemic collagen vascular disease and the clinical characteristics of patients presenting with non-infectious scleritis.
Sutasinee Boonsopon +4 more
doaj +1 more source
Turnover of type I and III collagen predicts progression of idiopathic pulmonary fibrosis
Respiratory Research, 2021 Background Idiopathic pulmonary fibrosis (IPF) is characterized by the accumulation of fibrillar collagens in the alveolar space resulting in reduced pulmonary function and a high mortality rate.
H. Jessen +8 more
doaj +1 more source
Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood. [PDF]
, 2016 Excess collagen synthesis (fibrogenesis) in the liver plays a causal role in the progression of nonalcoholic fatty liver disease (NAFLD). Methods are needed to identify patients with more rapidly progressing disease and to demonstrate early response to ...
Angel, Thomas E +16 more
core +1 more source