The Kidney in Collagen--Vascular Diseases [PDF]
David R. Turner
openalex +6 more sources
Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups [PDF]
Current diagnostic tests applied to inflammatory arthritis lack the necessary specificity to appropriately categorise patients. There is a need for novel approaches to classify patients with these conditions.
Gaya, Daniel+9 more
core +11 more sources
Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood. [PDF]
Excess collagen synthesis (fibrogenesis) in the liver plays a causal role in the progression of nonalcoholic fatty liver disease (NAFLD). Methods are needed to identify patients with more rapidly progressing disease and to demonstrate early response to ...
Angel, Thomas E+16 more
core +1 more source
Turnover of type I and III collagen predicts progression of idiopathic pulmonary fibrosis
Background Idiopathic pulmonary fibrosis (IPF) is characterized by the accumulation of fibrillar collagens in the alveolar space resulting in reduced pulmonary function and a high mortality rate.
H. Jessen+8 more
doaj +1 more source
Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke [PDF]
Haemorrhagic stroke accounts for approximately 20% of stroke cases and porencephaly is a clinical consequence of perinatal cerebral haemorrhaging. Here we report the identification of a novel dominant G702D mutation in the collagen domain of COL4A2 ...
Aislynn Taggart+35 more
core +1 more source
Collagens and collagen-related diseases
The collagen superfamily of proteins plays a dominant role in maintaining the integrity of various tissues and also has a number of other important functions. The superfamily now includes more than 20 collagen types with altogether at least 38 distinct polypeptide chains, and more than 15 additional proteins that have collagen-like domains.
Kari I. Kivirikko, Johanna Myllyharju
openaire +3 more sources
Non-Infectious Scleritis and Systemic Collagen Vascular Disease Association
Objective: To evaluate scleritis type in association with a systemic collagen vascular disease and the clinical characteristics of patients presenting with non-infectious scleritis.
Sutasinee Boonsopon+4 more
doaj +1 more source
Recent Developments in Osteogenesis Imperfecta [PDF]
Osteogenesis imperfecta (OI) is an uncommon genetic bone disease associated with brittle bones and fractures in children and adults. Although OI is most commonly associated with mutations of the genes for type I collagen, many other genes (some ...
Albert, Carolyne+3 more
core +2 more sources
Purpose: In elderly patients with collagen disease, walking ability tends to decrease due to treatment with corticosteroids and long-term hospitalization.
Shinya Yamauchi+4 more
doaj +1 more source
The role of collagen type I/III ratio in the etiology of sacrococcygeal pilonidal
Objective: The purpose of this study is to investigate whether there was a difference between the midline skin and the healthy skin in the lateral by means of total amount of collagen and Type I/III ratio which was the indicator of the collagen structure.
Arif Atay+4 more
doaj +1 more source