Results 211 to 220 of about 10,231,394 (364)

Biomimetic Fibrinogen Nanofiber Scaffolds for Vascular Hematopoietic Stem Cell Niche Engineering

Advanced Healthcare Materials, EarlyView.
This study presents an advanced in vitro model of the vascular hematopoietic stem cell niche using self‐assembled fibrinogen nanofibers, mimicking the basement membrane in bone marrow (BM) sinusoids. The model supports the coculture of microvascular endothelial cells, stromal cells, and hematopoietic stem and progenitor cells, providing insights into ...
Sophia Lena Meermeyer, Arundhati Joshi, Constantin von Kaisenberg, Dorothea Brüggemann, Cornelia Lee‐Thedieck   +4 more
wiley   +1 more source

Assessment of Collagen and Fibroblast Properties via Label-Free Higher Harmonic Generation Microscopy in Three-Dimensional Models of Osteogenesis Imperfecta and Ehlers-Danlos Syndrome. [PDF]

Int J Mol Sci
Ma Y, Bo Q, Zhang Z, van Haasterecht L, Kloen P, Rustemeyer T, Ventura L, Zhytnik L, Eekhoff EMW, Micha D, Groot ML.   +10 more
europepmc   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Engineered bone matrix models for understanding breast cancer skeletal metastasis. [PDF]

Cancer Metastasis Rev
Persson KM, Whitman MA, Fischbach C.
europepmc   +1 more source

Development of a Novel Synthetic Hydrogel Sealant for Effective Prevention of Liver Resection‐Associated Bile Leakage

Advanced Healthcare Materials, EarlyView.
A dual‐crosslinking poly(ethylene glycol) (PEG) hydrogel is presented that rapidly solidifies and progressively adheres to tissue, achieving durable sealing of bile leaks. In hepatectomy models, this system prevents postoperative complications more effectively than conventional sealants, highlighting its translational potential as a safe and efficient ...
Kazuyoshi Matsubara, Shohei Ishikawa, Hiroyuki Kamata, Almog Gur, Ayano Fujisawa, Shu Nishida, Katsuyuki Hoshina, Takamasa Sakai   +7 more
wiley   +1 more source

Depth-Wise Changes in Tibial and Femoral Human Knee Joint Cartilage at Different Severities of Osteoarthritis. [PDF]

J Orthop Res
Honkapää K, Eskelinen ASA, Mikkonen S, Ebrahimi M, Finnilä MAJ, Saarakkala S, Korhonen RK, Englund M, Tanska P.   +8 more
europepmc   +1 more source

Plasma collagen neoepitopes are associated with multiorgan disease in the ACCESS and GRADS sarcoidosis cohorts [PDF]

Jannie Marie Bülow Sand, Henrik Jessen, Diana Julie Leeming, Sheeline Yu, Chris Lee, Buqu Hu, Ying Sun, Taylor Adams, Taylor Pivarnik, Angela Liu, Samuel Woo, John McGovern, V. Fiorini, Tina Saber, Jean Paul Higuero-Sevilla, Mridu Gulati, Naftali Kaminski, William Damsky, Albert C. Shaw, Subhasis Mohanty, G.C. Goobie, Yingze Zhang, Erica L. Herzog, Changwan Ryu   +23 more
openalex   +1 more source

A Quantitative Printability Framework for Programmable Assembly of Pre‐Vascular Patterns via Laser‐Induced Forward Transfer

Advanced Healthcare Materials, EarlyView.
Laser‐Induced Forward Transfer (LIFT) is presented as a powerful micropatterning tool. An objective printability framework is developed to assess optimal printing parameter combinations. The technology is further explored for its ability to deterministically deposit microdroplets at predefined locations following CAD designs, enabling the patterning of
Cécile Bosmans, Núria Ginés Rodriguez, Ulisses Jesús Gutiérrez Hernández, David Fernandez Rivas, Marcel Karperien, Jos Malda, Liliana Moreira Teixeira, Riccardo Levato, Jeroen Leijten   +8 more
wiley   +1 more source

Palmar Fascia Fibrosis in Dupuytren's Disease: A Narrative Review of Pathogenic Mechanisms and Molecular Insights. [PDF]

Int J Mol Sci
Pirri C.
europepmc   +1 more source

Pathophysiology of Lung Disorders Associated with Collagen Disease

, 1995
Masaru Ando, Atsushi Sato, Sonoko Nagai, Hiroshi Hayakawa, Michito Hirakata, Shinichi Ishioka, Yoshihiro Nambu, Hajime Takizawa   +7 more
openalex   +2 more sources