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Collagens and collagen-related diseases

Annals of Medicine, 2001
The collagen superfamily of proteins plays a dominant role in maintaining the integrity of various tissues and also has a number of other important functions. The superfamily now includes more than 20 collagen types with altogether at least 38 distinct polypeptide chains, and more than 15 additional proteins that have collagen-like domains.
Johanna Myllyharju, Kari I Kivirikko, K I Kivirikko   +2 more
exaly   +3 more sources

Novel Approaches for the 3D Printing of Collagen-Sourced Biomaterials Against Infectious and Cardiovascular Diseases

Gels
Collagen is a versatile material, and collagen in the human body strengthens the muscles and related organs, allowing good substances to be absorbed into the bloodstream while preventing the absorption of toxic substances. Thus, collagen has been broadly
Yugyung Lee, Chi H. Lee
doaj   +3 more sources

Post-translational modifications of collagen and its related diseases in metabolic pathways

Acta Pharmaceutica Sinica B
As the most abundant and essential structural protein in the human body, collagen is ubiquitously present in the interstitium of nearly all solid organs, playing a crucial role in maintaining the structural integrity and functional stability of human ...
Linghong Guo, Weiyi Xiang, Zhaoping Pan, He Gu, Xian Jiang   +4 more
doaj   +3 more sources

Ventricular fibrillation immediately after the treatment of Graves’ disease coexisting with atypical angina and long QT syndrome: a case report

Thyroid Research, 2022
Background Palpitations due to Graves’ disease are often caused by supraventricular arrhythmia. However, in rare cases, the background of coronary artery disease, genetic abnormalities, or channel abnormalities can cause ventricular fibrillation, which ...
Hajime Iwasaki, Hirotsugu Suwanai, Hiroyuki Sakai, Keitaro Ishii, Natsuko Hara, Kazuhiro Satomi, Yasuyuki Takada, Yuki Nagamatsu, Ryo Suzuki   +8 more
doaj   +1 more source

Hypercalcemia associated with dysgerminoma and elevation of calcitriol: A case report and review of the literature

SAGE Open Medical Case Reports, 2022
We report on the case of a patient with dysgerminoma, a rare germ cell tumor, which showed hypercalcemia with an elevation of 1α,25-dihydroxycholecalciferol (calcitriol). A 27-year-old nulliparous woman presented with hypercalcemia during the examination
Natsuko Hara, Hirotsugu Suwanai, Hironori Abe, Fumiyoshi Yakou, Takuya Ishikawa, Munehiro Urayama, Takeshi Nagai, Toshitaka Nagao, Jumpei Shikuma, Takashi Miwa, Ryo Suzuki, Masato Odawara   +11 more
doaj   +1 more source

Serum progranulin level is a novel tool for monitoring disease activity of dermatomyositis with antimelanoma differentiation‐associated protein 5 antibodies

Journal of Cutaneous Immunology and Allergy, 2021
Objectives Dermatomyositis (DM) is an autoimmune disease that presents with a wide variety of clinical manifestations. Patients with DM or clinically amyopathic dermatomyositis (CADM) with antimelanoma differentiation‐associated protein 5 (anti‐MDA5 ...
Asami Fujii, Yuki H. Mizutani, Miho Kawamura, Kanako Matusyama, Yoko Mizutani, En Shu, Mariko Seishima   +6 more
doaj   +1 more source

Tofacitinib versus tocilizumab in the treatment of biological-naïve or previous biological-failure patients with methotrexate-refractory active rheumatoid arthritis

RMD Open, 2021
Objectives To compare effectiveness between tofacitinib and tocilizumab treatments for biological disease-modifying antirheumatic drug (bDMARD)-naïve patients or previous bDMARD-failure patients with active rheumatoid arthritis (RA) refractory to ...
Yukitaka Ueki, Yukitomo Urata, Shunsuke Mori, Tamami Yoshitama   +3 more
doaj   +1 more source

The presence of neutrophil extracellular traps in different forms of pyoderma gangrenosum

Journal of Cutaneous Immunology and Allergy, 2023
We demonstrated that there were abundant neutrophil extracellular traps (NETs) in the skin biopsies from various types of pyoderma gangrenosum (PG), based on the observation of extended and compact areas of immunolabeling of MPO and Cit H3 proteins.
Takaharu Ikeda, Tamihiro Kawakami, Kae Yokoyama, Yuka Nishibata, Sakiko Masuda, Utano Tomaru, Akihiro Ishizu   +6 more
doaj   +1 more source

Role of Collagen in Airway Mechanics

Bioengineering, 2021
Collagen is the most abundant airway extracellular matrix component and is the primary determinant of mechanical airway properties. Abnormal airway collagen deposition is associated with the pathogenesis and progression of airway disease.
Lumei Liu, Brooke Stephens, Maxwell Bergman, Anne May, Tendy Chiang   +4 more
doaj   +1 more source

Congenital collagenopathies increased the risk of inguinal hernia developing and repair: analysis from a nationwide population-based cohort study

Scientific Reports, 2022
Herein, we aimed to explore whether male patients with congenital collagen diseases had a higher risk of inguinal herniation than patients without these diseases. Data were retrospectively collected from the National Health Insurance Research Database of
Hao-Han Chang, Yung-Shun Juan, Ching-Chia Li, Hsiang-Ying Lee, Jian-Han Chen   +4 more
doaj   +1 more source