Results 41 to 50 of about 2,661,550 (300)

Comparison of the solophenyl-red polarization method and the immunohistochemical analysis for collagen type III [PDF]

open access: yes, 1992
In the present study, we have compared the staining pattern of the Solophenyl-Red 3 BL-method for the visualization of collagen type III with the immunohistochemical staining in serial sections from 7 skin wounds (wound age 3 days up to 4 weeks) to ...
Penning, R.   +5 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Delayed Diagnosis of Drug-induced Lung Disease Associated with Premature Closure Triggered by Masking

open access: yesJournal of Hospital General Medicine
A 73-year-old man developed drug-induced lung disease (DILD) during treatment with ampicillin and ceftriaxone for Enterococcus faecalis infective endocarditis.
Kengo Mukuda   +3 more
doaj   +1 more source

Matrix metalloproteinases (MMP-1, -8, -13) in chronic periapical lesions [PDF]

open access: yesVojnosanitetski Pregled, 2008
Background/Aim. Matrix metalloproteinases (MMPs) are proteolytic enzymes capable of degrading almost all extracellular matrix and basement membrane components in many destructive pathological processes, such as chronic inflammation and bone-destructive ...
Andonovska Biljana   +2 more
doaj   +1 more source

Hierarchical nanomechanics of collagen microfibrils [PDF]

open access: yes, 2010
Collagen constitutes one third of the human proteome, providing mechanical stability, elasticity and strength to connective tissues. Collagen is also the dominating material in the extracellular matrix (ECM) and is thus crucial for cell differentiation ...
Alberto Redaelli   +3 more
core  

The time-dependent rearrangement of the epithelial basement membrane in human skin wounds [PDF]

open access: yes, 1992
In 62 human skin wounds (surgical wounds, stab wounds and lacerations after surgical treatment) we analyzed the immunohistochemical localization of collagen IV in the epithelial basement membrane.
Penning, R.   +6 more
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Collagen of Dupuytren's Disease

open access: yesClinical Science, 1977
1. In contrast to collagen from the aponeurosis of normal adult subjects, the nodules, contractures and apparently unaffected aponeurosis from patients with Dupuytren's disease contained substantial amounts of type III collagen. 2. The presence of type III collagen supports the previous proposal that the initial response to injury is the
Bailey, A. J.   +4 more
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Contribution of postnatal collagen reorientation to depth-dependent mechanical properties of articular cartilage [PDF]

open access: yes, 2011
The collagen fibril network is an important factor for the depth-dependent mechanical behaviour of adult articular cartilage (AC). Recent studies show that collagen orientation is parallel to the articular surface throughout the tissue depth in perinatal
Kranenbarg, S.   +2 more
core   +1 more source

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