Results 51 to 60 of about 2,661,550 (300)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Beyond classical collagen: basement membrane collagen IV in age-associated lung diseases
European Respiratory ReviewChronic lung diseases such as COPD, asthma, idiopathic pulmonary fibrosis (IPF) and pulmonary hypertension are characterised by aberrant remodelling and degradation of the extracellular matrix.
Natalia El-Merhie +3 more
doaj +1 more source
Fluorescent spectroscopy of collagen as a diagnostic tool in medicine
Journal of Medical Science, 2022 Medicine continuously needs to improve the existing diagnostic solutions or introduce new ones. Despite the fact that collagen is a well described protein, collagen-related diseases represent the disorders requiring improvement particularly in terms of ...
Łukasz Saletnik, Roland Wesołowski
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Materials Today BioThe accurate detection of multiplex collagen biomarkers is vital for diagnosing and treating various critical diseases such as tumors and fibrosis. Despite the attractive optical properties of quantum dots (QDs), it remains technically challenging to ...
Xiangdong Cai +7 more
doaj +1 more source
PLoS ONE, 2017 Dysregulation of collagen production contributes to various pathological processes, including tissue fibrosis as well as impaired wound healing.
Yoolhee Yang +4 more
doaj +1 more source
Collagen-Based Biomaterials for Tissue Engineering
, 2023 Collagen is commonly used as a regenerative biomaterial due to its excellent biocompatibility and wide distribution in tissues. Different kinds of hybridization or cross-links are favored to offer improvements to satisfy various needs of biomedical ...
Yan Dong (135314) +2 more
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of IL-10-producing B cells and reduced plasma cell infiltration of the joints [PDF]
, 2014 We have previously reported that ES-62, a molecule secreted by the parasitic filarial nematode Acanthocheilonema viteae, protects mice from developing collagen-induced arthritis (CIA).
Al-Riyami, Lamyaa +5 more
core +4 more sources
Endostatin in Renal and Cardiovascular Diseases
Kidney Diseases, 2021 Endostatin, a protein derived from the cleavage of collagen XVIII by the action of proteases, is an endogenous inhibitor known for its ability to inhibit proliferation and migration of endothelial cells, angiogenesis, and tumor growth.
Mei Li +4 more
doaj +1 more source