Results 31 to 40 of about 2,661,550 (300)

Early Detection and Staging of Lung Fibrosis Enabled by Collagen-Targeted MRI Protein Contrast Agent

Chemical & Biomedical Imaging, 2023
Chronic lung diseases, such as idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD), are major leading causes of death worldwide and are generally associated with poor prognoses. The heterogeneous distribution of collagen,
Oluwatosin Y. Ibhagui, Dongjun Li, Hongwei Han, Guangda Peng, Maureen L. Meister, Zongxiang Gui, Jingjuan Qiao, Mani Salarian, Bin Dong, Yi Yuan, Yiting Xu, Hua Yang, Shanshan Tan, Ganesh Satyanarayana, Shenghui Xue, Ravi Chakra Turaga, Malvika Sharma, Yan Hai, Yuguang Meng, Khan Hekmatyar, Phillip Sun, Gabriel Sica, Xiangming Ji, Zhi-ren Liu, Jenny J. Yang   +24 more
doaj   +1 more source

Immunohistochemical localization of collagen types I and VI in human skin wounds [PDF]

, 1996
A total of 74 human skin wounds were investigated and collagen types I and VI were localized in the wound area by immunohistochemistry. Collagen type I appeared in the form of ramifying string-like structures after approximately 5–6 days, but positive ...
Penning, R., Eisenmenger, Wolfgang, Nerlich, A., Tübel, J., Wilske, J., Betz, P.   +5 more
core   +1 more source

Visualization and phenotyping of proinflammatory antigen-specific T cells during collagen-induced arthritis in a mouse with a fixed collagen type II-specific transgenic T-cell receptor beta-chain [PDF]

, 2010
Introduction: The Vbeta12-transgenic mouse was previously generated to investigate the role of antigen-specific T cells in collagen-induced arthritis (CIA), an animal model for rheumatoid arthritis. This mouse expresses a transgenic collagen type II (CII)
Burkhardt, H, Dzhambazov, Balik, Bockermann, Robert, Bettina Sehnert, Batsalova, Tsvetelina, Harald Burkhardt, Burkhardt, Harald, Robert Bockermann, Baecklund, Johan, Batsalova, T, Bockermann, R, Dzhambazov, B, Merky, Patrick, Baecklund, J, Bäcklund, Johan, Sehnert, B, Patrick Merky, Sehnert, Bettina, Balik Dzhambazov, Tsvetelina Batsalova, Lund University., Johan Backlund, Merky, P,, Bockermann, Robert,   +23 more
core   +1 more source

Detecting Collagen Molecules at Picogram Level through Electric Field-Induced Accumulation

Sensors, 2020
The demand for sensors capable of measuring low-abundant collagen in human fluids has highly increased in recent years. Indeed, collagen is expected to be a biomarker for chronic diseases and could monitor their progression.
Romina Rega, Martina Mugnano, Emilia Oleandro, Volodymyr Tkachenko, Danila del Giudice, Gianluca Bagnato, Pietro Ferraro, Simonetta Grilli, Sebastiano Gangemi   +8 more
doaj   +1 more source

Second harmonic generation confocal microscopy of collagen type I from rat tendon cryosections [PDF]

, 2006
We performed second harmonic generation (SHG) imaging of collagen in rat-tendon cryosections, using femtosecond laser scanning confocal microscopy, both in backscattering and transmission geometries.
Theodossiou, Theodossis A., Thrasivoulou, C, Chidi Ekwobi, Ekwobi, Chidi, Theodossiou, TA, Becker, DL, Becker, David L., David L. Becker, Christopher Thrasivoulou, Thrasivoulou, Christopher, Theodossis A. Theodossiou, Ekwobi, C   +11 more
core   +1 more source

In vivo generation of collagen specific Tregs with AAV8 suppresses autoimmune responses and arthritis in DBA1 mice through IL10 production

Scientific Reports, 2021
Available therapeutics for autoimmune disorders focused on mitigating symptoms, rather than treating the cause of the disorder. A novel approach using adeno-associated virus (AAV) could restore tolerance to the autoimmune targets and provide a permanent ...
Matthew Wade, Hugues Fausther-Bovendo, Marc-Antoine De La Vega, Gary Kobinger   +3 more
doaj   +1 more source

Review of the role of collagen in tumorigenesis and development

Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Collagen is one of the most abundant proteins in the body and is the main component of the extracellular matrix. Collagen regulates cellular behavior, and its dysregulation can cause a variety of diseases, including cancer.
TANG Lei, XU Yingchun, ZHANG Fengchun
doaj   +1 more source

Plasmid-Encoded Outer Membrane Protein YadA Mediates Specific Binding of Enteropathogenic Yersiniae to Various Types of Collagen [PDF]

, 1992
The plasmid-encoded outer membrane protein YadA of enteropathogenic yersiniae is associated with pathogenicity. Recently, collagen binding of YadA-positive yersiniae was reported without detailed characterization (L. Emödy, J. Heesemann, H. Wolf-Watz, M.
Emmerich, F., Burkhardt, H., Schulze-Koops, Hendrik, Heesemann, Jürgen, Mark, K. von der   +4 more
core   +1 more source

Where to Shop For GVP Collagen Retinol Moisturising Cream?

, 2020
In any case, some foe of developing conditions are exorbitantly relieving and sensitive. Thusly, while they may feel conventional and immerse your skin, they're not generally viably fight signs of developing.
GVP Collagen Retinol
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source