Results 21 to 30 of about 346,226 (309)

Collagen XVII Processing and Blistering Skin Diseases

open access: yesActa Dermato-Venereologica, 2020
Collagen XVII (COL17) is a hemidesmosomal transmembrane protein in the skin, which, in several autoimmune blistering skin diseases, may be targeted by autoantibodies.
Wataru Nishie
doaj   +1 more source

Anemia revealing a collagenous gastritis in a young Tunisian man

open access: yesThe Pan African Medical Journal, 2018
Collagenous gastritis is a rare entity, characterized by the deposition of a subepithelial collagenous band with an inflammatory infiltrate in the mucosa. We report the first Tunisian case revealed by severe anemia.
Imen Akkari   +4 more
doaj   +1 more source

Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of IL-10-producing B cells and reduced plasma cell infiltration of the joints [PDF]

open access: yes, 2014
We have previously reported that ES-62, a molecule secreted by the parasitic filarial nematode Acanthocheilonema viteae, protects mice from developing collagen-induced arthritis (CIA).
Harnett, M.M.   +17 more
core   +1 more source

Early Detection and Staging of Lung Fibrosis Enabled by Collagen-Targeted MRI Protein Contrast Agent

open access: yesChemical & Biomedical Imaging, 2023
Chronic lung diseases, such as idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD), are major leading causes of death worldwide and are generally associated with poor prognoses. The heterogeneous distribution of collagen,
Oluwatosin Y. Ibhagui   +24 more
doaj   +1 more source

Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage [PDF]

open access: yes, 2015
20 páginas, 4 figuras, 3 tablas y 7 tablas en material suplementario.Snake venom hemorrhagic metalloproteinases (SVMPs) of the PI, PII and PIII classes were compared in terms of tissue localization and their ability to hydrolyze basement membrane ...
Calvete, JJ   +47 more
core   +1 more source

Review of the role of collagen in tumorigenesis and development

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Collagen is one of the most abundant proteins in the body and is the main component of the extracellular matrix. Collagen regulates cellular behavior, and its dysregulation can cause a variety of diseases, including cancer.
TANG Lei, XU Yingchun, ZHANG Fengchun
doaj   +1 more source

Detecting Collagen Molecules at Picogram Level through Electric Field-Induced Accumulation

open access: yesSensors, 2020
The demand for sensors capable of measuring low-abundant collagen in human fluids has highly increased in recent years. Indeed, collagen is expected to be a biomarker for chronic diseases and could monitor their progression.
Romina Rega   +8 more
doaj   +1 more source

In vivo generation of collagen specific Tregs with AAV8 suppresses autoimmune responses and arthritis in DBA1 mice through IL10 production

open access: yesScientific Reports, 2021
Available therapeutics for autoimmune disorders focused on mitigating symptoms, rather than treating the cause of the disorder. A novel approach using adeno-associated virus (AAV) could restore tolerance to the autoimmune targets and provide a permanent ...
Matthew Wade   +3 more
doaj   +1 more source

ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta [PDF]

open access: yes, 2008
Osteogenesis imperfecta is an inherited disorder characterized by increased bone fragility, fractures, and osteoporosis, and most cases are caused by mutations affecting the type I collagen genes.
Ralston, Stuart H.   +55 more
core   +1 more source

Matrix metalloproteinases (MMP-1, -8, -13) in chronic periapical lesions [PDF]

open access: yesVojnosanitetski Pregled, 2008
Background/Aim. Matrix metalloproteinases (MMPs) are proteolytic enzymes capable of degrading almost all extracellular matrix and basement membrane components in many destructive pathological processes, such as chronic inflammation and bone-destructive ...
Andonovska Biljana   +2 more
doaj   +1 more source

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