Beyond classical collagen: basement membrane collagen IV in age-associated lung diseases [PDF]
Chronic lung diseases such as COPD, asthma, idiopathic pulmonary fibrosis (IPF) and pulmonary hypertension are characterised by aberrant remodelling and degradation of the extracellular matrix.
Natalia El-Merhie +3 more
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A study of Pulmonary Manifestations in Collagen Vascular Diseases
Introduction: Collagen vascular diseases are group of diseases with specific characteristics. Pulmonary manifestations are com- monly present in collagen Vascular Diseases.
Parul Vadgama, Pankaj Garg
doaj +1 more source
Collagen is a versatile material, and collagen in the human body strengthens the muscles and related organs, allowing good substances to be absorbed into the bloodstream while preventing the absorption of toxic substances. Thus, collagen has been broadly
Yugyung Lee, Chi H. Lee
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Current treatment strategies: Collagen vascular diseases in children
Of the various collagen vascular diseases seen in pediatric age group, discoid lupus erythematosus, systemic lupus erythematosus, neonatal lupus erythematosus, juvenile dermatomyositis and childhood scleroderma are common and of practical importance to ...
Aparna Palit, Arun C Inamadar
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Collagen IV-related diseases and therapies [PDF]
While traditionally the function of the extracellular matrix and the basement membrane was considered to be providing structural support, it is now clear that this only covers one aspect of its multiple functions.
Tom Van Agtmael +3 more
core +1 more source
Postnatal development of depth-dependent collagen density in ovine articular cartilage [PDF]
Articular cartilage (AC) is the layer of tissue that covers the articulating ends of the bones in diarthrodial joints. Adult AC is characterised by a depth-dependent composition and structure of the extracellular matrix that results in depth-dependent ...
Kranenbarg, S. +24 more
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Epicutaneous immunization with type II collagen inhibits both onset and progression of chronic collagen-induced arthritis. [PDF]
Epicutaneous immunization is a potential non-invasive technique for antigen-specific immune-modulation. Topical application of protein antigens to barrier-disrupted skin induces potent antigen-specific immunity with a strong Th2-bias.
Strobel, S +9 more
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Visualization and phenotyping of proinflammatory antigen-specific T cells during collagen-induced arthritis in a mouse with a fixed collagen type II-specific transgenic T-cell receptor beta-chain [PDF]
Introduction: The Vbeta12-transgenic mouse was previously generated to investigate the role of antigen-specific T cells in collagen-induced arthritis (CIA), an animal model for rheumatoid arthritis. This mouse expresses a transgenic collagen type II (CII)
Burkhardt, H +23 more
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Targeting inflammation with collagen
Tissue damage caused by an infection or an autoimmune disease triggers degradation of collagen in the extracellular matrix (ECM), which further enhances inflammation.
Dennis Schwarz +3 more
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The time-dependent rearrangement of the epithelial basement membrane in human skin wounds [PDF]
In 62 human skin wounds (surgical wounds, stab wounds and lacerations after surgical treatment) we analyzed the immunohistochemical localization of collagen IV in the epithelial basement membrane.
Penning, R. +6 more
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