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Collagens and collagen-related diseases
The collagen superfamily of proteins plays a dominant role in maintaining the integrity of various tissues and also has a number of other important functions. The superfamily now includes more than 20 collagen types with altogether at least 38 distinct polypeptide chains, and more than 15 additional proteins that have collagen-like domains.
J, Myllyharju, K I, Kivirikko
openaire +4 more sources
Post-translational modifications of collagen and its related diseases in metabolic pathways
As the most abundant and essential structural protein in the human body, collagen is ubiquitously present in the interstitium of nearly all solid organs, playing a crucial role in maintaining the structural integrity and functional stability of human ...
Linghong Guo +4 more
doaj +3 more sources
Characterisation of collagen-derived biomaterials [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University on 22 May 2009.One of the main problems in healthcare is the loss or failure of organs or tissues resulting from diseases, post-surgery complications ...
de Castro Bras, Lisandra
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A study of Pulmonary Manifestations in Collagen Vascular Diseases
Introduction: Collagen vascular diseases are group of diseases with specific characteristics. Pulmonary manifestations are com- monly present in collagen Vascular Diseases.
Parul Vadgama, Pankaj Garg
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Background Palpitations due to Graves’ disease are often caused by supraventricular arrhythmia. However, in rare cases, the background of coronary artery disease, genetic abnormalities, or channel abnormalities can cause ventricular fibrillation, which ...
Hajime Iwasaki +8 more
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We report on the case of a patient with dysgerminoma, a rare germ cell tumor, which showed hypercalcemia with an elevation of 1α,25-dihydroxycholecalciferol (calcitriol). A 27-year-old nulliparous woman presented with hypercalcemia during the examination
Natsuko Hara +11 more
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Objectives Dermatomyositis (DM) is an autoimmune disease that presents with a wide variety of clinical manifestations. Patients with DM or clinically amyopathic dermatomyositis (CADM) with antimelanoma differentiation‐associated protein 5 (anti‐MDA5 ...
Asami Fujii +6 more
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Objectives To compare effectiveness between tofacitinib and tocilizumab treatments for biological disease-modifying antirheumatic drug (bDMARD)-naïve patients or previous bDMARD-failure patients with active rheumatoid arthritis (RA) refractory to ...
Yukitaka Ueki +3 more
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The presence of neutrophil extracellular traps in different forms of pyoderma gangrenosum
We demonstrated that there were abundant neutrophil extracellular traps (NETs) in the skin biopsies from various types of pyoderma gangrenosum (PG), based on the observation of extended and compact areas of immunolabeling of MPO and Cit H3 proteins.
Takaharu Ikeda +6 more
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Role of Collagen in Airway Mechanics
Collagen is the most abundant airway extracellular matrix component and is the primary determinant of mechanical airway properties. Abnormal airway collagen deposition is associated with the pathogenesis and progression of airway disease.
Lumei Liu +4 more
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