Results 21 to 30 of about 10,231,394 (364)
A role for collagen type IV in cardiovascular disease?
American Journal of Physiology. Heart and Circulatory Physiology, 2018 Over the past decade, studies have repeatedly found single-nucleotide polymorphisms located in the collagen ( COL) 4A1 and COL4A2 genes to be associated with cardiovascular disease (CVD), and the 13q34 locus harboring these genes is one of ~160 genome ...
L. Steffensen, L. Rasmussen
semanticscholar +1 more source
Genotype-phenotype correlation study in 364 osteogenesis imperfecta Italian patients [PDF]
, 2019 Osteogenesis imperfecta (OI) is a rare genetic disorder of the connective tissue and 90% of cases are due to dominant mutations in COL1A1 and COL1A2 genes.
Boarini, Manila +11 more
core +1 more source
Oral‐bacterial‐induced arterial and venous thrombus in rats: Pathological and immunological studies
Clinical and Experimental Dental Research, 2019 Objectives Our study investigated the pathological outcome of experimental thrombi that incorporate oral bacteria. Material and methods A small artery and vein in the rats' groins were injected with a solution containing periodontal bacteria ...
Takehisa Iwai +7 more
doaj +1 more source
Collagens and collagen-related diseases
Annals of Medicine, 2001 The collagen superfamily of proteins plays a dominant role in maintaining the integrity of various tissues and also has a number of other important functions. The superfamily now includes more than 20 collagen types with altogether at least 38 distinct polypeptide chains, and more than 15 additional proteins that have collagen-like domains.
J, Myllyharju, K I, Kivirikko
openaire +2 more sources
Revista Brasileira de Reumatologia, 2004 O lúpus eritematoso (LE) raramente ocorre na infância e, quando aparece, manifesta-se, mais freqüentemente, sob a forma de lúpus eritematoso sistêmico.
Marlene Freire +5 more
doaj +1 more source
The role of collagen type I/III ratio in the etiology of sacrococcygeal pilonidal
Cirugía y Cirujanos, 2022 Objective: The purpose of this study is to investigate whether there was a difference between the midline skin and the healthy skin in the lateral by means of total amount of collagen and Type I/III ratio which was the indicator of the collagen structure.
Arif Atay +4 more
doaj +1 more source
Role of growth factors in the pathogenesis of tissue fibrosis in systemic sclerosis. [PDF]
, 2010 The most severe clinical and pathologic manifestations of systemic sclerosis (SSc) are the result of a fibrotic process characterized by the excessive and often progressive deposition of collagen and other connective tissue macromolecules in skin and ...
Castro, Susan V. +2 more
core +2 more sources
Plasma Amino Acid Profiles in Collagen Disease Patients with Interstitial Lung Disease
, 2013 Interstitial lung disease (ILD) is frequently associated with collagen diseases, and is designated collagen vascular disease-associated ILD (CVD-ILD) that influences the prognosis of the disease.
H. Furukawa +8 more
semanticscholar +1 more source
In Vivo Fluorescence Imaging of E-Selectin: Quantitative Detection of Endothelial Activation in Arthritis [PDF]
, 2010 Rheumatoid arthritis (RA) is a chronic progressive systemic inflammatory disease, characterized by synovial inflammation and localized destruction of cartilage and bone.
Gompels, Luke, Gompels, Luke
core +1 more source
Congenic mice confirm that collagen X is required for proper hematopoietic development. [PDF]
PLoS ONE, 2010 The link between endochondral skeletal development and hematopoiesis in the marrow was established in the collagen X transgenic (Tg) and null (KO) mice. Disrupted function of collagen X, a major hypertrophic cartilage matrix protein, resulted in skeletal
Elizabeth Sweeney +3 more
doaj +1 more source