Results 31 to 40 of about 10,231,394 (364)

Teflon Injection into the Trachea Causes Predictable Fibroblastic Response and Collagen Deposition: A Pilot Study. [PDF]

, 2016
BackgroundExpiratory central airway collapse is an increasingly recognized abnormality of the central airways and may be present in as many as 22% of patients evaluated for chronic obstructive pulmonary disease and/or asthma.
Baxter, Boiselle, Bolliger, Bolot, Chertin, Chertin, Dedo, Eisner, Ernst, Ernst, Feist, Ferguson, Fujiwara, Gilkeson, Ikeda, Iwamoto, Johnson, Jokinen, Jokinen, Kirchner, Lehman, Majid, Murgu, Noppen, Nuutinen, Palombini, Susanto, Wright, Zhang   +28 more
core   +1 more source

Elevated levels of β-catenin and fibronectin in three-dimensional collagen cultures of Dupuytren's disease cells are regulated by tension in vitro

BMC Musculoskeletal Disorders, 2003
Background Dupuytren's contracture or disease (DD) is a fibro-proliferative disease of the hand that results in the development of scar-like, collagen-rich disease cords within specific palmar fascia bands.
Varallo Vincenzo M, Howard Jeffrey C, Ross Douglas C, Roth James H, Faber Kenneth J, Alman Benjamin, Gan Bing   +6 more
doaj   +1 more source

Fibrotic and Vascular Remodelling of Colonic Wall in Patients with Active Ulcerative Colitis [PDF]

, 2016
open16noIntestinal fibrosis is a complication of inflammatory bowel disease [IBD]. Although fibrostenosis is a rare event in ulcerative colitis [UC], there is evidence that a fibrotic rearrangement of the colon occurs in the later stages.
Bassotti, Gabrio, Bernardini, Nunzia, Blandizzi, Corrado, Buccianti, Piero, Campani, Daniela, Castagna, Maura, Colucci, Rocchina, Di Candio, Giulio, Dolfi, Amelio, ERREDE, Mariella, GIROLAMO, FRANCESCO, Ippolito, Chiara, Segnani, Cristina, Tirotta, Erika, Villanacci, Vincenzo, VIRGINTINO, Daniela   +15 more
core   +2 more sources

Collagen Structure-Function Mapping Informs Applications for Regenerative Medicine

Bioengineering, 2020
Type I collagen, the predominant protein of vertebrates, assembles into fibrils that orchestrate the form and function of bone, tendon, skin, and other tissues.
James D. San Antonio, Olena Jacenko, Andrzej Fertala, Joseph P.R.O. Orgel   +3 more
doaj   +1 more source

Collagen XII mediated cellular and extracellular mechanisms in development, regeneration, and disease

Frontiers in Cell and Developmental Biology, 2023
Collagen XII, a fibril-associated collagen with interrupted triple helices (FACIT), influences fibrillogenesis in numerous tissues. In addition to this extracellular function, collagen XII also directly regulates cellular function. Collagen XII is widely
Yayoi Izu, David E. Birk
doaj   +1 more source

Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis

Nature Communications, 2020
Collagen-producing cells maintain the complex architecture of the lung and drive pathologic scarring in pulmonary fibrosis. Here we perform single-cell RNA-sequencing to identify all collagen-producing cells in normal and fibrotic lungs.
T. Tsukui, Kai-Hui Sun, Joseph B. Wetter, J. Wilson-Kanamori, L. Hazelwood, Neil C. Henderson, Taylor Sterling Adams, Jonas C. Schupp, S. Poli, Ivan O. Rosas, N. Kaminski, M. Matthay, Paul J. Wolters, Dean Sheppard   +13 more
semanticscholar   +1 more source

The parasitic worm product ES-62 up-regulates IL-22 production by γδ T cells in the murine model of Collagen-Induced Arthritis [PDF]

, 2014
S-62 is a phosphorylcholine (PC)-containing glycoprotein secreted by the filarial nematode Acanthocheilonema viteae that acts to modulate the host immune response to promote the establishment of chronic helminth infection.
Harnett, Margaret, Harnett, William, Pineda, Miguel Angel   +2 more
core   +1 more source

Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1 [PDF]

, 2018
Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matrix in renal fibrosis is ...
A Clayton, A Desmouliere, A Holmes, A Yabuki, AA Eddy, AA Eddy, AC Sanchez-Lara, BL Aken, C Grupp, C. P. D. Wheeler-Jones, CH Heldin, CL Marino, E Honda, E Van Obberghen-Schilling, F Strutz, F Strutz, F Syeda, GR Grotendorst, H. M. Syme, HP Rodemann, J Ivaska, J Lu, J. Elliott, J. S. Lawson, JL Mumaw, JS Lawson, K Sawashima, KG McCullagh, KJ Kelynack, LC Penning, M Prunotto, M Zeisberg, MA Venkatachalam, MJ Ryan, MK Phanish, ML Sequeira Lopez, P Boor, P Sysa, PC Bartlett, Q Chai, RA Ignotz, S Chakrabarti, S Meran, S Moll, S Neelisetty, SC Chen, SL Lin, SP DiBartola, SW Smith, T Akamatsu, TA Wynn, V Dugina, VS Lebleu, W Bloom, WA Border, X Pan, XM Meng, Y Hosokawa, Y Liu   +58 more
core   +2 more sources

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis [PDF]

, 2012
Idiopathic pulmonary fibrosis (IPF) is a fatal disease that is unresponsive to current therapies and characterized by excessive collagen deposition and subsequent fibrosis.
Anderson, G.P., Bozinovski, S., Ernst, M.R., Jarnicki, A.G., Jones, J., Knight, D.A., Lau, H.L., Laurent, G.J., McAnulty, R.J., McKenzie, B.S., Mutsaers, S.E., O'Donoghue, R.J.J., Prêle, C.M., Richards, C.D., Rose-John, S., Stumbles, P.A., Thiem, S., Vlahos, R., Wang, B., Zhu, H.J.   +19 more
core   +2 more sources

Targeting inflammation with collagen

Clinical and Translational Medicine, 2022
Tissue damage caused by an infection or an autoimmune disease triggers degradation of collagen in the extracellular matrix (ECM), which further enhances inflammation.
Dennis Schwarz, Marie Lipoldová, Holger Reinecke, Yahya Sohrabi   +3 more
doaj   +1 more source