Results 141 to 150 of about 515,691 (319)

Role of Deleterious Rare Alleles for Acute-Onset Diffuse Interstitial Lung Disease in Collagen Diseases. [PDF]

open access: yesClin Med Insights Circ Respir Pulm Med, 2019
Furukawa H   +6 more
europepmc   +1 more source

A Computational Journey Toward an Optimal Design for Metamaterial Epicardial Passive Sleeves

open access: yesAdvanced Healthcare Materials, EarlyView.
Passive epicardial sleeves are evaluated in 3D in‐silico heart models to reveal how sleeve geometry, stiffness, anisotropy, and metamaterial architecture influence cardiac mechanics after myocardial infarction. A continuum‐to‐auxetic design exploration shows that region‐specific mechanical engagement can reduce infarct bulging and modulate torsional ...
Vahid Naeini   +8 more
wiley   +1 more source

Chemical Tools for Monitoring and Targeting Collagen Cross-linking

open access: yesCHIMIA
The formation of collagen, the most abundant protein in mammals, is vital for the integrity of skin, tendons, and tissue in essentially any organ. Excessive collagen formation is, however, characteristic of fibrotic and malignant diseases, which include ...
Matthew C. Deen   +2 more
doaj   +1 more source

P30  Evaluating the potential of cis- and trans-4-[ 18 F]fluoro-L-proline positron emission tomography as biomarkers of active collagen biosynthesis in cardiometabolic diseases [PDF]

open access: bronze
Angus Jacobs   +19 more
openalex   +1 more source

Effect of 2D and 3D ECM and Biomechanical Cues on Human iPSC‐Derived Liver Progenitor Cell Differentiation

open access: yesAdvanced Healthcare Materials, EarlyView.
An engineered microtissue model is developed and optimized to investigate human liver development. Extracellular matrix composition and mechanical forces are tuned using high‐throughput assays. Human induced pluripotent stem cells serve as the cellular source, enabling the observation of de novo patterned differentiation.
Ishita Jain   +5 more
wiley   +1 more source

Binding Truths: Atypical Anti−Glomerular Basement Membrane Disease Mediated by IgA Anti−Glomerular Basement Membrane Antibodies Targeting the α1 Chain of Type IV Collagen [PDF]

open access: gold, 2018
Marilina Antonelou   +7 more
openalex   +1 more source

A Human Neural Tube Model Using 4D Self‐Folding Smart Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
Induced pluripotent stem cells (iPSCs) exhibit features comparable to the inner cell mass of the human embryo. iPSCs are applied to a novel self‐folding 4D‐Neural Tube (4D‐NT) structure that mimics the neurulation process. This 4D‐NT model recapitulates early events of human neural development and represents a platform to explore neurodevelopmental ...
Claudia Dell'Amico   +8 more
wiley   +1 more source

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