Results 171 to 180 of about 322,215 (278)

Hybrid Scaffolds Decouple Biochemical & Biophysical Regulation of Cell Phenotype

open access: yesAdvanced Healthcare Materials, EarlyView.
Replicating tissue‐specific extracellular matrix is crucial for understanding its role in disease. This work demonstrates independent control over stiffness, composition and 3D collagen architecture using hybrid scaffolds: patterned collagen perfused with defined hydrogels.
Xinyuan Song   +17 more
wiley   +1 more source

Macrophages and TGFB signaling regulate fibrosis in the <i>Escherichia coli</i>-infected mouse prostate. [PDF]

open access: yesAm J Physiol Renal Physiol
Scharpf BR   +17 more
europepmc   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim   +6 more
wiley   +1 more source

Heterogeneity in Histological Evaluation of Microscopic Colitis in Randomized Clinical Trials: An Umbrella Review. [PDF]

open access: yesInflamm Bowel Dis
Yuan Y   +7 more
europepmc   +1 more source

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady   +5 more
wiley   +1 more source

Collagen XII is Commonly Downregulated in the Dermal Extracellular Matrix in Diverse Skin Pathologies. [PDF]

open access: yesMedComm (2020)
Martins L   +6 more
europepmc   +1 more source

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