Results 251 to 260 of about 515,691 (319)

LGALS3 promotes liver fibrosis by enhancing the expression and phosphorylation of ERK1/2. [PDF]

Eur J Med Res
Zheng X, Yang L, Wang W, Sun J, Li Y.
europepmc   +1 more source

Defects In The Biochemistry Of Collagen In Diseases Of Connective Tissue

, 1976
Jouni Uitto, J R Lichtenstein
openalex   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Collagen XII Plays a More Prominent Cell-Mediated Role in Tendon Organization Compared to Matrix Assembly During Postnatal Development. [PDF]

FASEB J
Fung AK, Weiss SN, Nuss CA, Yen W, Volk SW, Dyment NA, Soslowsky LJ.   +6 more
europepmc   +1 more source

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Naringenin attenuates liver injury in Schistosoma mansoni-induced liver fibrosis and oxidative stress in mice model. [PDF]

PLoS Negl Trop Dis
Liang TR, Liu CZ, Peng SY.
europepmc   +1 more source

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

Mesenchymal stromal cells ameliorate systemic sclerosis-interstitial lung disease via PD-1/PD-L1 signalling axis. [PDF]

RMD Open
Chen Y, Zhu H, Zhang Y, Liu M, Wu Y, Ding S, Wang D, Sun L.   +7 more
europepmc   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Extracellular matrix dysregulation in aging, calcification, and cancer diseases: insights into cellular senescence, inflammation, and novel therapeutic strategies. [PDF]

Int J Biol Sci
Boaru DL, De Leon-Oliva D, De Castro-Martinez P, Garcia-Montero C, Fraile-Martinez O, García-González B, Pérez-González I, Alhaddadin MNM, Barrena-Blázquez S, Lopez-Gonzalez L, de la Torre B, Pekarek L, Saez MA, Ríos-Espinosa L, Pekarek T, de la Sacristana RFG, Hernández-Fernández M, Casanova C, Castel-Oñate A, Garcia-Honduvilla N, Buján J, Diaz-Pedrero R, Alvarez-Mon M, Ortega MA.   +23 more
europepmc   +1 more source