Results 91 to 100 of about 23,206 (306)
Failure of Mineralized Collagen Microfibrils Using Finite Element Simulation Coupled to Mechanical Quasi-brittle Damage [PDF]
Bone is a multiscale heterogeneous materiel of which principal function is to support the body structure and to resist mechanical loading and fractures. Bone strength does not depend only on the quantity and quality of bone which is characterized by the ...
Abdelwahed Barkaoui+23 more
core +2 more sources
Autonomous Control of Extrusion Bioprinting Using Convolutional Neural Networks
This work presents a novel computer vision system for high‐fidelity monitoring of extrusion‐based bioprinting and a correction system utilizing convolutional neural networks for error mitigation. This system has demonstrated high detection accuracy and extrusion correction abilities that advance the state of the art toward accelerated printing ...
Daniel Kelly+4 more
wiley +1 more source
Helical mutations in type I collagen that affect the processing of the amino-propeptide result in an Osteogenesis Imperfecta/Ehlers-Danlos Syndrome overlap syndrome [PDF]
Background: Whereas mutations affecting the helical domain of type I procollagen classically cause Osteogenesis Imperfecta (OI), helical mutations near the amino (N)-proteinase cleavage site have been suggested to result in a mixed OI/Ehlers-Danlos ...
De Paepe, Anne+9 more
core +2 more sources
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana+2 more
wiley +1 more source
Posttraumatic fibrotic scarring is a significant medical problem that alters the proper functioning of injured tissues. Current methods to reduce posttraumatic fibrosis rely on anti-inflammatory and anti-proliferative agents with broad intracellular ...
Andrzej Steplewski+10 more
doaj +1 more source
Alginate-Collagen Fibril Composite Hydrogel [PDF]
We report on the synthesis and the mechanical characterization of an alginate-collagen fibril composite hydrogel. Native type I collagen fibrils were used to synthesize the fibrous composite hydrogel. We characterized the mechanical properties of the fabricated fibrous hydrogel using tensile testing; rheometry and atomic force microscope (AFM)-based ...
Baniasadi, Mahmoud+1 more
openaire +3 more sources
An anisotropic microsphere-based approach for fiber orientation adaptation in soft tissue [PDF]
Evolutionary processes in biological tissue, such as adaptation or remodeling, represent an enterprising area of research. In this paper, we present a multiscale model for the remodeling of fibered structures, such as bundles of collagen fibrils.
Doblaré, Manuel+3 more
core +2 more sources
A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari+11 more
wiley +1 more source
Collagen self-assembly on orthopedic magnesium biomaterials surface and subsequent bone cell attachment. [PDF]
Magnesium (Mg) biomaterials are a new generation of biodegradable materials and have promising potential for orthopedic applications. After implantation in bone tissues, these materials will directly interact with extracellular matrix (ECM) biomolecules ...
Nan Zhao, Donghui Zhu
doaj +1 more source
Tunable Thermoshrinkable Hydrogels for 4D Fabrication of Cell‐Seeded Channels
A thermoresponsive polymer with methacrylate groups for photo‐cross‐linking, based on polyethylene glycol, N‐isopropylacrylamide, and 2‐hydroxyethyl acrylate is synthetized to yield hydrogels that shrink upon temperature increase. The new polymer enables the fabrication of cell‐laden perfusable channels with diameters below 200 µm by combining ...
Greta Di Marco+12 more
wiley +1 more source